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view test-data/2019-08-27.1/changes.txt @ 3:dddde93d5c20
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| author | estrain |
|---|---|
| date | Fri, 06 Mar 2020 10:43:40 -0500 |
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--------------------------------------------------------------------- Changes included in 2019-08-27.1 --------------------------------------------------------------------- This release includes a new database file to correspond with AMRFinderPlus version 3.1 that includes information for blacklisting of a few "plus" proteins common in some organisms that are interesting when found in others. This release also includes the usual new AMR genes and alleles; the fixing of some typos; removal of a redundant point mutation reference sequence; and the addition, reoorganization, and renaming of some "plus" genes. - Reference Gene Catalog protein and allele changes: Total in prev: 6110 Total in release: 6274 Removed: 18 Added: 182 Changed: 33 Removed emrD3 WP_000850833.1 Removed blaOXA-671 WP_016660101.1 Removed arsB-mob WP_063116263.1 Removed gyrA_A67S WP_001281242.1 Removed gyrA_A84P WP_001281242.1 Removed gyrA_D87G WP_001281242.1 Removed gyrA_D87H WP_001281242.1 Removed gyrA_D87N WP_001281242.1 Removed gyrA_D87V WP_001281242.1 Removed gyrA_D87Y WP_001281242.1 Removed gyrA_G81C WP_001281242.1 Removed gyrA_H80P WP_001281242.1 Removed gyrA_N57K WP_001281242.1 Removed gyrA_Q106H WP_001281242.1 Removed gyrA_S83F WP_001281242.1 Removed gyrA_S83I WP_001281242.1 Removed gyrA_S83L WP_001281242.1 Removed gyrA_S83W WP_001281242.1 Added arsB AAA21095.1 Added arsC AAA21096.1 Added arsR AAA25636.1 Added arsB AAA25637.1 Added copC AAA25808.1 Added arsR AAA27587.1 Added arsB AAA27588.1 Added arsR AAB09624.1 Added arsC AAB09628.1 Added arsC AAB42203.1 Added arsB AAB42204.1 Added ipaH9.8 AAC23714.1 Added pic AAD23953.1 Added efa1 AAD49229.2 Added iha AAG55323.1 Added stb AAK29747.1 Added efa1 AAL57562.1 Added pic AAN78833.1 Added iha AAN82058.1 Added cif AAQ07241.1 Added iha AAT68782.1 Added efa1 AAV91321.1 Added sab AAZ76500.1 Added senB AAZ89288.1 Added iha ABB17254.1 Added emrD3 ABQ18953.1 Added kdeA ABR76310.1 Added lmrC ABX00624.1 Added iha ACB20136.1 Added iha ACD08748.1 Added amvA ACQ82816.1 Added ipaH4 ADA74402.1 Added iha ADI47068.1 Added iha ADN47767.1 Added arsR ADZ44504.1 Added iha AEQ14190.1 Added stb AET14866.1 Added arsR AET17094.1 Added pic AFS72825.1 Added iha AFS75030.1 Added asr BAA15331.2 Added arsB BAA24823.1 Added arsC BAA24824.1 Added espK BAB34991.1 Added fieF BAB89353.1 Added fieF BAE77395.1 Added arsR BAE77793.1 Added cif BAG66370.1 Added iha BAI27255.1 Added efa1 BAI32294.1 Added iha CAC39288.1 Added efa1 CAC81883.1 Added efa1 CAD30848.1 Added stb CAD87835.1 Added iha CAE55782.1 Added efa1 CAI43818.1 Added hlyA-alpha CAQ77251.1 Added iha CAR09712.2 Added pic CAU99295.1 Added iha CBW53086.1 Added ipaH5 EID63069.1 Added fosB WP_000920239.1 Added dfrA36 WP_000949574.1 Added mphM WP_001041372.1 Added cfr(B) WP_002405682.1 Added mphK WP_003246254.1 Added blaPDC-374 WP_003454242.1 Added tet(56) WP_003635403.1 Added blaCDD-1 WP_009901927.1 Added mphH WP_015776248.1 Added erm(49) WP_019728092.1 Added blaCDD-2 WP_021361759.1 Added mphN WP_024127776.1 Added tet(X) WP_024160783.1 Added blaPDC-361 WP_031638595.1 Added tet(G) WP_032489471.1 Added vga(E) WP_032495718.1 Added blaACT-72 WP_045895620.1 Added blaACT-70 WP_047364854.1 Added blaACT-69 WP_048209719.1 Added ble WP_063842967.1 Added blaOXA-671 WP_081401608.1 Added icr-Mo WP_082741435.1 Added blaOXA-653 WP_087554513.1 Added tet(X) WP_094309310.1 Added blaMOX-13 WP_096807444.1 Added blaFOX-15 WP_096807445.1 Added blaCMY-157 WP_096807446.1 Added blaIMP-69 WP_099156051.1 Added blaPDC-249 WP_104009845.1 Added blaACT-58 WP_111965422.1 Added blaACT-62 WP_111967096.1 Added blaACT-63 WP_112780466.1 Added blaOXA-727 WP_114272532.1 Added blaOXA-731 WP_116786833.1 Added blaOXA-728 WP_116786835.1 Added blaPDC-367 WP_121286063.1 Added blaPDC-364 WP_121347819.1 Added blaFLC-1 WP_123061077.1 Added blaPDC-371 WP_126118969.1 Added blaPDC-353 WP_128550481.1 Added blaVIM-67 WP_142875125.1 Added blaADC-196 WP_145850033.1 Added blaAQU WP_148044401.1 Added blaAQU WP_148044402.1 Added dfrA29 WP_148044403.1 Added blaCAM-1 WP_148044405.1 Added blaCMY-165 WP_148044406.1 Added blaCMY-166 WP_148044407.1 Added blaCMY-167 WP_148044408.1 Added blaCTX-M-227 WP_148044409.1 Added blaCTX-M-228 WP_148044410.1 Added blaCTX-M-229 WP_148044411.1 Added blaDHA-29 WP_148044412.1 Added blaGES-42 WP_148044413.1 Added blaGES-43 WP_148044414.1 Added blaIMP-82 WP_148044416.1 Added blaIMP-83 WP_148044417.1 Added blaIMP-84 WP_148044418.1 Added blaKPC-41 WP_148044419.1 Added blaKPC-45 WP_148044420.1 Added blaKPC-46 WP_148044421.1 Added blaOXA-835 WP_148044422.1 Added blaOXA-836 WP_148044423.1 Added blaPAU-1 WP_148044424.1 Added blaPDC-196 WP_148044425.1 Added blaPDC-334 WP_148044426.1 Added blaPDC-335 WP_148044427.1 Added blaPDC-336 WP_148044428.1 Added blaPDC-337 WP_148044429.1 Added blaPDC-338 WP_148044430.1 Added blaPDC-339 WP_148044431.1 Added blaPDC-340 WP_148044432.1 Added blaPDC-341 WP_148044433.1 Added blaPDC-342 WP_148044434.1 Added blaPDC-343 WP_148044435.1 Added blaPDC-344 WP_148044436.1 Added blaPDC-345 WP_148044437.1 Added blaPDC-346 WP_148044438.1 Added blaPDC-347 WP_148044439.1 Added blaPDC-348 WP_148044440.1 Added blaPDC-349 WP_148044441.1 Added blaPDC-350 WP_148044442.1 Added blaPDC-351 WP_148044443.1 Added blaPDC-352 WP_148044444.1 Added blaPDC-354 WP_148044445.1 Added blaPDC-355 WP_148044446.1 Added blaPDC-356 WP_148044447.1 Added blaPDC-357 WP_148044448.1 Added blaPDC-358 WP_148044449.1 Added blaPDC-359 WP_148044450.1 Added blaPDC-360 WP_148044451.1 Added blaPDC-362 WP_148044452.1 Added blaPDC-363 WP_148044453.1 Added blaPDC-365 WP_148044454.1 Added blaPDC-366 WP_148044455.1 Added blaPDC-368 WP_148044456.1 Added blaPDC-369 WP_148044457.1 Added blaPDC-370 WP_148044458.1 Added blaPDC-372 WP_148044459.1 Added blaPDC-373 WP_148044460.1 Added blaPDC-375 WP_148044461.1 Added blaPDC-376 WP_148044462.1 Added blaPDC-377 WP_148044463.1 Added blaPDC-378 WP_148044464.1 Added blaPDC-379 WP_148044465.1 Added blaPDC-380 WP_148044466.1 Added blaPDC-381 WP_148044467.1 Added blaPDC-382 WP_148044468.1 Added blaPDC-383 WP_148044469.1 Added blaPFM-1 WP_148044470.1 Added blaTEM-241 WP_148044472.1 Added blaTEM-242 WP_148044473.1 Added blaTEM-39 WP_148044474.1 Added blaVEB-22 WP_148044475.1 Added blaVIM-68 WP_148044476.1 Added mcr-1.22 WP_148044477.1 Added mcr-5.4 WP_148044478.1 Added blaOXA-837 WP_148281568.1 Added gyrA_H80P WP_001281243.1 Added gyrA_N57K WP_001281243.1 Added gyrA_S83F WP_001281243.1 Changes: faeG AAA24032.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG AAA24035.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG AAA24390.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG nccX AAA65102.1 subclass METAL -> merB AAA88369.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merC AAC33908.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY faeG AAC34727.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG merB AAC38230.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merC AAC38233.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY ipaH2 AAN43435.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 mreA AAN68577.1 subclass METAL -> ipaH2 AAZ87985.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 ipaH3 ABB62096.1 gene_family ipaH9.8 -> ipaH3 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH3 ipaH2 ABB62098.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 ipaH2 ABB66229.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 ipaH1 ABF02983.1 gene_family ipaH9.8 -> ipaH1 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH1/H6 ipaH2 ABF04028.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 faeG ACB72721.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG ipaH2 ACD09076.1 gene_family ipaH9.8 -> ipaH2 product_name T3SS effector E3 ubiquitin-protein ligase IpaH9.8 -> T3SS effector E3 ubiquitin-protein ligase IpaH2 faeG AFH14350.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG merC BAA14138.2 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merB BAA20338.2 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merG BAA23166.1 class MECURY -> MERCURY merB BAB47641.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY merB CAC86907.1 class MECURY -> MERCURY subclass ORGANOMECURY -> ORGANOMERCURY faeG CAE82650.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG CAE82653.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG faeG CAE82670.1 product_name F4 fimbrial adhesin subunit FaeG -> F4 (K88) fimbrial adhesin subunit FaeG mphL WP_002047670.1 gene_family mph(B) -> mphL product_name Mph(B) family macrolide 2'-phosphotransferase -> macrolide 2'-phosphotransferase MphL poxtA WP_002415638.1 genbank_cds_start 1856 -> 57639 genbank_cds_stop 3484 -> 59267 genbank_nucleotide_accession MF095097.1 -> MH746818.1 mcr-3.22 WP_094308975.1 refseq_nucleotide_accession NG_060581.1 -> NG_060581.2 blaPDC-259 WP_109791193.1 genbank_nucleotide_accession MH243333.1 -> MH243333.2 refseq_nucleotide_accession NG_057591.1 -> NG_057591.2 blaPDC-265 WP_109791199.1 genbank_nucleotide_accession MH243339.1 -> MH243339.2 refseq_nucleotide_accession NG_057597.1 -> NG_057597.2 - HMM library Changes: Total: Added 6 Total: Prev. Release 603 Total: Removed 1 Total: This Release 608 HMM Removed: NF000274.2 PF04439 HMM Added: NF007456.1 PRK10026.1 HMM Added: NF033636.1 acid_shock_Asr HMM Added: NF033877.0 arsB_Sta_pI258 HMM Added: NF033895.1 blaCAM HMM Added: NF033929.1 blaAXC HMM Added: NF033933.0 fosA8 - Protein family changes: Total: Added 47 Total: Prev. Release 1454 Total: Removed 1 Total: This Release 1500 Family Removed: - ubiq_IpaH3 Family Added: - ACID Family Added: - CDF_efflux Family Added: - amvA Family Added: NF033877.0 arsB_pI258 Family Added: - arsB_pKW301 Family Added: - arsB_pYV Family Added: NF007456.1 arsC_gluta Family Added: - arsR Family Added: - arsR_K-12 Family Added: - arsR_R46 Family Added: - arsR_pI258 Family Added: - arsR_pKW301 Family Added: - arsR_pSX267 Family Added: - arsR_pYV Family Added: NF033636.1 asr Family Added: NF033929.1 blaAXC Family Added: NF033895.1 blaCAM Family Added: - blaPFM Family Added: - cif Family Added: - copC_Psyr Family Added: - dfrA29 Family Added: - efa1 Family Added: - erm(49) Family Added: - espK Family Added: - fieF Family Added: NF033933.0 fosA8 Family Added: - hlyA-alpha Family Added: - icr-Mo Family Added: - iha Family Added: - ipaH1 Family Added: - ipaH2 Family Added: - ipaH3 Family Added: - ipaH4 Family Added: - ipaH5 Family Added: - ipa_gen Family Added: - kdeA Family Added: - lmrC_abcf Family Added: - mphH Family Added: - mphK Family Added: - mphL Family Added: - mphM Family Added: - mphN Family Added: - pic_auto Family Added: - sab Family Added: - senB Family Added: - stb Family Added: - tet(56) Family Changed: NF000274.2 ant6_gen updated to - ant6_gen --------------------------------------------------------------------- Changes included in 2019-07-10.1 --------------------------------------------------------------------- New alleles and sequences were added, a few product names were made more specific as more phenotype information became available. Cleanup of the database caused some families and HMMs not used by AMRFinderPlus to be removed. - Protein changes: Total: Added 57 Total: Prev. Release 5757 Total: Removed 3 Total: This Release 5811 Protein Removed: WP_029728367.1 blaB BlaB_family_subclass_B1_metallo-beta-lactamase Protein Removed: WP_063842622.1 blaB BlaB_family_subclass_B1_metallo-beta-lactamase Protein Removed: WP_063842629.1 blaGOB GOB_family_subclass_B3_metallo-beta-lactamase Protein Added: AAA21095.1 arsB_R773 arsenite_efflux_transporter_membrane_subunit_ArsB Protein Added: ABQ18953.1 emrD3 multidrug_efflux_MFS_transporter_EmrD-3 Protein Added: WP_000850833.1 emrD3 multidrug_efflux_MFS_transporter_EmrD-3 Protein Added: WP_010446567.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) Protein Added: WP_039902635.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-646 Protein Added: WP_063116263.1 arsB_R773 arsenite_efflux_transporter_membrane_subunit_ArsB Protein Added: WP_063844329.1 dfrA12 trimethoprim-resistant_dihydrofolate_reductase_DfrA12 Protein Added: WP_063856066.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) Protein Added: WP_063856068.1 tet(B) tetracycline_efflux_MFS_transporter_Tet(B) Protein Added: WP_070342370.1 dfrA7 trimethoprim-resistant_dihydrofolate_reductase_DfrA7 Protein Added: WP_071593205.1 aadA1bt ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt Protein Added: WP_071593208.1 aadA1bt ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1bt Protein Added: WP_086264536.1 blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-832 Protein Added: WP_094323230.1 mcr-2 phosphoethanolamine--lipid_A_transferase_MCR-2.3 Protein Added: WP_110174956.1 blaTEM class_A_beta-lactamase_TEM-235 Protein Added: WP_125052736.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-834 Protein Added: WP_129336087.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.19 Protein Added: WP_135350920.1 blaGES class_A_beta-lactamase_GES-41 Protein Added: WP_140423191.1 aac(6')-Ib AAC(6')-Ib_family_aminoglycoside_6'-N-acetyltransferase Protein Added: WP_140423278.1 aadA1 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA1 Protein Added: WP_140423279.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 Protein Added: WP_140423280.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 Protein Added: WP_140423281.1 aadA2 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA2 Protein Added: WP_140423282.1 aadA5 ANT(3'')-Ia_family_aminoglycoside_nucleotidyltransferase_AadA5 Protein Added: WP_140423283.1 dfrA1 trimethoprim-resistant_dihydrofolate_reductase_DfrA1 Protein Added: WP_140423284.1 dfrA12 trimethoprim-resistant_dihydrofolate_reductase_DfrA12 Protein Added: WP_140423285.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 Protein Added: WP_140423286.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 Protein Added: WP_140423287.1 dfrA17 trimethoprim-resistant_dihydrofolate_reductase_DfrA17 Protein Added: WP_140423305.1 blaADC class_C_beta-lactamase_ADC-195 Protein Added: WP_140423306.1 blaB subclass_B1_metallo-beta-lactamase_BlaB-15 Protein Added: WP_140423307.1 blaCMY class_C_beta-lactamase_CMY-164 Protein Added: WP_140423308.1 blaFRI carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-8 Protein Added: WP_140423309.1 blaFRI carbapenem-hydrolyzing_class_A_beta-lactamase_FRI-9 Protein Added: WP_140423310.1 blaIMI carbapenem-hydrolyzing_class_A_beta-lactamase_IMI-19 Protein Added: WP_140423311.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-44 Protein Added: WP_140423312.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-643 Protein Added: WP_140423313.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-644 Protein Added: WP_140423314.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-645 Protein Added: WP_140423315.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-647 Protein Added: WP_140423316.1 blaOXA-134_like OXA-134_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-648 Protein Added: WP_140423317.1 blaOXA-211_like OXA-211_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-650 Protein Added: WP_140423318.1 blaOXA-143_like OXA-143_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-825 Protein Added: WP_140423319.1 blaOXA-213_like OXA-213_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-826 Protein Added: WP_140423320.1 blaOXA-10_like OXA-10_family_class_D_beta-lactamase_OXA-827 Protein Added: WP_140423321.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-828 Protein Added: WP_140423322.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-829 Protein Added: WP_140423323.1 blaOXA-51_like OXA-51_family_carbapenem-hydrolyzing_class_D_beta-lactamase_OXA-831 Protein Added: WP_140423324.1 blaOXA-48_like OXA-48_family_class_D_beta-lactamase_OXA-833 Protein Added: WP_140423325.1 blaPDC class_C_beta-lactamase_PDC-333 Protein Added: WP_140423326.1 blaPOM subclass_B3_metallo-beta-lactamase_POM-2 Protein Added: WP_140423327.1 blaVIM subclass_B1_metallo-beta-lactamase_VIM-64 Protein Added: WP_140423328.1 blaVIM subclass_B1_metallo-beta-lactamase_VIM-65 Protein Added: WP_140423329.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.20 Protein Added: WP_140423330.1 mcr-1 phosphoethanolamine--lipid_A_transferase_MCR-1.21 Protein Added: WP_140423331.1 mcr-3 phosphoethanolamine--lipid_A_transferase_MCR-3.26 Protein Added: WP_140423332.1 mcr-3 phosphoethanolamine--lipid_A_transferase_MCR-3.30 Protein Modified: ACM67153.1 lamda-2 intimin_type_lambda updated to ACM67153.1 lambda-2 intimin_type_lambda Protein Modified: WP_001100753.1 blaPER class_A_extended-spectrum_beta-lactamase_PER-1 updated to WP_001100753.1 blaPER inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_PER-1 Protein Modified: WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002317273.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_002368697.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_032489743.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856719.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856723.1 vanR-B VanB-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_DNA-binding_response_regulator_VanR updated to WP_063856729.1 vanR-O VanO-type_vancomycin_resistance_response_regulator_transcription_factor_VanR Protein Modified: WP_063860636.1 blaKPC carbapenem-hydrolyzing_class_A_beta-lactamase_KPC-14 updated to WP_063860636.1 blaKPC inhibitor-resistant_class_A_extended-spectrum_beta-lactamase_KPC-14 - AMR HMM library Changes: Total: Added 5 Total: Prev. Release 610 Total: Removed 12 Total: This Release 603 HMM Removed: NF000252.1 MexX HMM Removed: NF000282.2 RND_permease_1 HMM Removed: NF000314.1 adeB HMM Removed: NF000315.1 adeC-adeK-oprM HMM Removed: NF007842.1 PRK10555.1 HMM Removed: NF011706.2 PRK15127.1 HMM Removed: NF028537.1 P_eth_NH2_trans HMM Removed: NF033086.2 penta_rpt_Qnr HMM Removed: NF033134.0 cmlA_floR HMM Removed: NF033143.1 efflux_OM_AdeK HMM Removed: NF033643.1 EspJ_gen HMM Removed: NF033651.1 cyto_nec_fctrs HMM Added: NF000478.2 linco_LnuE HMM Added: NF012180.1 tet_MFS_43 HMM Added: NF033866.1 blaCDD HMM Added: NF033867.1 blaPAU HMM Added: NF033868.0 trim_DfrA36 - Protein family changes: Total: Added 11 Total: Prev. Release 1449 Total: Removed 6 Total: This Release 1454 Family Removed: NF011706.2 acrB Family Removed: NF007842.1 acrD Family Removed: NF000314.1 adeB/adeJ Family Removed: NF033143.1 adeK Family Removed: - lamda Family Removed: - lamda-2 Family Added: - aadA1bt Family Added: - arsB Family Added: - arsB_R773 Family Added: NF033866.1 blaCDD Family Added: NF033867.1 blaPAU Family Added: NF033868.0 dfrA36 Family Added: - emrD3 Family Added: - lambda Family Added: - lambda-2 Family Added: NF000478.2 lnu(E) Family Added: NF012180.1 tet(43) Family Changed: NF030466.1 MerP_Gneg updated to TIGR02052.1 MerP_Gneg Family Changed: NF030467.1 merA updated to TIGR02053.1 merA --------------------------------------------------------------------- Changes included in 2019-06-18.1 --------------------------------------------------------------------- This the first alpha release of the AMRFinderPlus database. For this and all following releases there is a distinction between "core" proteins which correspond to the genes that would previously have been reported by AMRFinder and "plus" proteins that are new genes and classes of genes. The "core" designation is given to proteins where we believe their presence is likely to have an important effect on antimicrobial resistance. * Screen for select point mutations for antibiotic resistance from Salmonella, E. coli, and Campylobacter * Protein mutations in: 50S_L22 protein, acrB, acrR, basR, cmeR, cyaA, fabG, fabI, folP, gyrA, gyrB, lon, marR, murA, nfsA, ompF, parC, parE, pmrA, pmrB, ptsI, ramR, rpoB, rpsL, soxR, soxS, tufA, uhpA, uhpT * Nucleotide mutations in 16S and 23S rRNA * Included point mutations are listed in the reference gene database (https://www.ncbi.nlm.nih.gov/pathogens/isolates#/refgene/) * New "Plus" genes * virulence factors * biocide resistance * metal resistance * heat resistance * acid resistance * Combined and integrated results from nucleotide and protein searches File formats have changed significantly. See https://github.com/evolarjun/amr/wiki for details. Since release 2019-04-29.1 only one change has been made to the core AMR proteins. Qac's are now categorized under Type STRESS and Subtype BIOCIDE. - Protein changes: Prev. Release: 4942 This Release: 5718 Added: 776 Modified: 0 Protein Added: ABF69110.1 eae intimin type beta Protein Added: ABF69117.1 eae intimin type epsilon Protein Added: ABF69121.1 eae intimin type epsilon Protein Added: ABF69122.1 eae intimin type alpha Protein Added: KYU89760.1 subB subtilase AB5 cytotoxin subunit B Protein Added: AAG16664.1 perA BFP system transcriptional regulator PerA Protein Added: AAG16667.1 perA BFP system transcriptional regulator PerA Protein Added: AAG16676.1 perA BFP system transcriptional regulator PerA Protein Added: AAB09625.1 arsD arsenite efflux transporter metallochaperone ArsD Protein Added: AAB09626.1 arsA arsenite efflux transporter ATPase subunit ArsA Protein Added: CAJ76690.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAJ76692.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: AAA98291.1 terC tellurium resistance membrane protein TerC Protein Added: AAA98293.1 terE tellurium resistance cAMP binding protein TerE Protein Added: AAG27731.1 norM sodium-coupled multidrug efflux MATE transporter NorM Protein Added: ABF02983.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABF04028.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: BAE98279.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: BAE98281.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: CAC14596.1 smeF multidrug efflux RND transporter outer membrane subunit SmeF Protein Added: AAA83973.1 merR1 mercury resistance transcriptional regulator MerR1 Protein Added: AAA83975.1 merT mercuric transport protein MerT Protein Added: AAA98292.1 terD tellurium resistance membrane protein TerD Protein Added: AAG34504.1 perA BFP system transcriptional regulator PerA Protein Added: APX31172.1 yfdX1 heat resistance protein YfdX1 Protein Added: APX31174.1 hdeD-GI heat resistance membrane protein HdeD-GI Protein Added: APX31176.1 trxLHR heat resistance system thioredoxin Trx-GI Protein Added: APX31177.1 kefB-GI heat resistance system K+/H+ antiporter KefB-GI Protein Added: APX31178.1 psi-GI heat resistance protein PsiE-GI Protein Added: AAA85087.1 f17a F17A fimbrial adhesin Protein Added: AAA85196.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: AAG37043.1 espC serine protease autotransporter toxin EspC Protein Added: ABI93207.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: BAF33872.1 capU putative hexosyltransferase CapU Protein Added: BAF33878.1 aggR aggregative adherence transcriptional regulator AggR Protein Added: BAF33885.1 sepA serine protease autotransporter toxin SepA Protein Added: BAF33888.1 agg4D aggregative adherence fimbria 4 chaperone Agg4D/HdaD Protein Added: BAF33891.1 agg4A aggregative adherence fimbria 4 major subunit Agg4A/HdaA Protein Added: BAF33901.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: BAF34018.1 aap dispersin Aap Protein Added: ABJ00546.1 iss increased serum survival lipoprotein Iss Protein Added: ABJ02430.1 ireA TonB-dependent siderophore receptor IreA Protein Added: OPH66324.1 lpfA1 long polar fimbria major subunit LpfA1 Protein Added: ABJ90288.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAA86846.1 terZ tellurium resistance-associated protein TerZ Protein Added: ABC67318.2 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAG40758.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAA88371.1 merE broad-spectrum mercury transporter MerE Protein Added: AAG42788.1 perA BFP system transcriptional regulator PerA Protein Added: ASF80766.1 yfdX2 heat resistance protein YfdX2 Protein Added: ASF80771.1 shsP small heat shock protein sHSP20-GI Protein Added: CAM11313.1 nleA type III secretion system effector NleA Protein Added: CAM11314.1 nleA type III secretion system effector NleA Protein Added: CAM11315.1 nleA type III secretion system effector NleA Protein Added: CAM11317.1 nleA type III secretion system effector NleA Protein Added: CAM11321.1 nleA type III secretion system effector NleA Protein Added: CAM11323.1 nleA type III secretion system effector NleA Protein Added: CAM11324.1 nleA type III secretion system effector NleA Protein Added: CAM11325.1 nleA type III secretion system effector NleA Protein Added: AAA92618.1 f17a F17A fimbrial adhesin Protein Added: AAA92621.1 f17g F17G fimbrial adhesin Protein Added: AAA93060.1 arsD arsenite efflux transporter metallochaperone ArsD Protein Added: AAG53662.1 perA BFP system transcriptional regulator PerA Protein Added: BAF45432.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: BAF45437.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45439.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45440.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45447.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45451.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF45459.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: ABM90581.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90583.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90587.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90589.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90597.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90605.1 perA BFP system transcriptional regulator PerA Protein Added: ABM90615.1 perA BFP system transcriptional regulator PerA Protein Added: AAC46147.1 yfeA iron/manganese ABC transporter substrate-binding protein YfeA Protein Added: AAC46148.1 yfeB iron/manganese ABC transporter ATP-binding protein YfeB Protein Added: AAC46150.1 yfeD iron/manganese ABC transporter permease subunit YfeD Protein Added: ATE69525.1 acr3 arsenite efflux transporter Acr3 Protein Added: AAG55141.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: AAG56990.1 espJ type III secretion system effector ADP-ribosyltransferase EspJ Protein Added: AAG58695.1 lpfA1 long polar fimbria major subunit LpfA1 Protein Added: AAG58814.1 espF type III secretion system LEE effector EspF Protein Added: AAG58818.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAG58825.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAK15050.1 ttgR efflux transport transcriptional regulator TtgR Protein Added: AAK16940.1 nleA type III secretion system effector NleA Protein Added: AAK17180.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: AAK18385.1 sepA serine protease autotransporter toxin SepA Protein Added: AAK18444.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: BAB37280.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAB38093.1 lpfA2 long polar fimbria major subunit LpfA2 Protein Added: AAC44736.1 terW tellurium resistance protein TerW Protein Added: AVL28824.1 aar AggR-activated transcriptional regulator Aar Protein Added: SPD96882.1 silS copper/silver sensor histidine kinase SilS Protein Added: SPD96883.1 silR copper/silver response regulator transcription factor SilR Protein Added: SPD96884.1 silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC Protein Added: CAA57177.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA57175.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA57173.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA57171.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: BAB43874.1 cadD cadmium resistance transporter CadD Protein Added: AAK48830.1 cadR cadmium resistance transcriptional regulator CadR Protein Added: BAF52034.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52035.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52033.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52358.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52360.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52362.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52363.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52364.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52365.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52366.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52367.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52370.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52374.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52377.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAF52548.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: BAF52549.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: BAB47641.1 merB organomercurial lyase MerB Protein Added: AAK56853.1 chrR class I chromate reductase ChrR Protein Added: CAC39286.1 espI serine protease autotransporter EspI Protein Added: AAA83977.1 merA mercury(II) reductase Protein Added: AAA23405.1 fasA F6 fimbrial major subunit FasA Protein Added: AAA23421.1 fim41a fimbrial adhesin F41 protein Fim41a Protein Added: AAK66972.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAC41416.1 cfaC CFA/I pilus usher protein CfaC Protein Added: CAB54534.2 mchB microcin H47 Protein Added: AAK69562.1 srpS solvent efflux transporter transcriptional repressor SrpS Protein Added: AAA23734.1 fedA F18 fimbrial major subunit FedA Protein Added: ABQ02454.1 eae intimin type rho Protein Added: AAA24032.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAA24035.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAA24390.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AXV27948.1 agg3C aggregative adherence fimbria 3 usher protein Agg3C Protein Added: AAA19189.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAA19190.1 stx2Be Shiga toxin Stx2e subunit B Protein Added: AAA24632.1 stx2Af Shiga toxin Stx2f subunit A Protein Added: AAA24633.1 stx2Bf Shiga toxin Stx2f subunit B Protein Added: AAA71893.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: AAA71894.1 stx1Ba Shiga toxin Stx1a subunit B Protein Added: AAA24653.1 sta1 heat-stable enterotoxin ST-I group a Protein Added: ABR09925.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR09934.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ABR09935.1 stx2Bc Shiga toxin Stx2c subunit B Protein Added: ABR09936.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: ABR09937.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: ABR09945.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR09961.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR09963.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: ABR10024.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAA30714.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: CAA30715.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: AAB59075.1 merT mercuric transport protein MerT Protein Added: AAA88369.1 merB organomercurial lyase MerB Protein Added: AAA88370.1 merD mercury resistance co-regulator MerD Protein Added: AAA98222.1 merT mercuric transport protein MerT Protein Added: AAA98223.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: AAA25638.1 arsC thioredoxin-dependent arsenate reductase Protein Added: AAA88432.1 chrA chromate resistance efflux protein ChrA Protein Added: AAA25803.1 copR heavy metal response regulator transcription factor CopR Protein Added: AAA25804.1 copS copper resistance membrane spanning protein CopS Protein Added: AAA25806.1 copA laccase-like oxidase CopA Protein Added: AAA25807.1 copB copper-binding protein CopB Protein Added: CAC48396.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAC48398.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAA21094.1 arsA arsenite efflux transporter ATPase subunit ArsA Protein Added: BAB62897.1 cofA type IV pilus CFA/III major pilin Protein Added: BAB62907.1 cofA type IV pilus CFA/III major pilin Protein Added: CAA63849.1 ehxA enterohemolysin Protein Added: AAA26402.1 klaB tellurium resistance system protein klaB Protein Added: AAA26403.1 klaC tellurium resistance system protein klaC Protein Added: AAK97136.1 cfaC CFA/I pilus usher protein CfaC Protein Added: AAK99679.1 pmrA multidrug efflux MFS transporter PmrA Protein Added: CAC69248.1 merR mercury resistance transcriptional regulator MerR Protein Added: CAC69249.1 merT mercuric transport protein MerT Protein Added: CAC69250.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: CAC69251.1 merA mercury(II) reductase Protein Added: BAB64566.1 bexA multidrug efflux MATE transporter BexA Protein Added: AAA27589.1 arsC thioredoxin-dependent arsenate reductase Protein Added: ABU55302.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: BAF76383.1 ttgA toluene efflux RND transporter periplasmic adaptor subunit TtgA Protein Added: BAF76384.1 ttgB multidrug efflux RND transporter permease subunit TtgB Protein Added: ABV01314.1 ltcA heat-labile enterotoxin LT subunit A Protein Added: BAF79679.1 smdA multidrug efflux ABC transporter permease/ATP-binding subunit SmdA Protein Added: BAF79680.1 smdB multidrug efflux ABC transporter permease/ATP-binding subunit SmdB Protein Added: ABV16438.1 eatA serine protease autotransporter toxin EatA Protein Added: BAB68369.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: BAB68370.1 stx2Bc Shiga toxin Stx2c subunit B Protein Added: BAF80121.1 ssmE multidrug efflux SMR transporter SsmE Protein Added: AAL06376.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAL06381.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AAL06387.1 espF type III secretion system LEE effector EspF Protein Added: AAC23256.1 hmrM sodium-coupled multidrug efflux MATE transporter HmrM Protein Added: ABQ02442.1 ehxA enterohemolysin Protein Added: ABQ02443.1 ehxA enterohemolysin Protein Added: ABQ02445.1 ehxA enterohemolysin Protein Added: ABQ02447.1 ehxA enterohemolysin Protein Added: ABQ02448.1 ehxA enterohemolysin Protein Added: AAL08400.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: BAF92845.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAL14441.1 adeC multidrug efflux RND transporter AdeABC outer membrane channel subunit AdeC Protein Added: CAP17609.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAP17610.1 stx2Be Shiga toxin Stx2e subunit B Protein Added: AAL18821.1 epeA serine protease autotransporter EpeA Protein Added: AAL19305.1 mdsB multidrug efflux RND transporter permease subunit MdsB Protein Added: AAL19306.1 mdsA multidrug efflux RND transporter periplasmic adaptor subunit MdsA Protein Added: AAL19307.1 golT gold/copper-translocating P-type ATPase GolT Protein Added: AAL19308.1 golS Au(I) sensor transcriptional regulator GolS Protein Added: BAF96525.1 espJ type III secretion system effector ADP-ribosyltransferase EspJ Protein Added: BAF96538.1 nleB2 type III secretion system effector arginine glycosyltransferase NleB2 Protein Added: BAF96541.1 nleA type III secretion system effector NleA Protein Added: BAA18405.1 acr3 arsenite efflux transporter Acr3 Protein Added: BAA18407.1 arsC thioredoxin-dependent arsenate reductase Protein Added: AAL26283.1 saa autoagglutinating adhesin Saa Protein Added: CAA65654.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAC45964.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAC45965.1 stx2Be Shiga toxin Stx2e subunit B Protein Added: ACA34793.1 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh Protein Added: BAG11995.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: BAG11997.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: BAG12001.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: ACB16424.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: ACB16655.1 eilA HilA family transcriptional regulator EilA Protein Added: ACB17037.1 air inverse autotransporter adhesin EaeX/Air Protein Added: CAA70196.1 merT mercuric transport protein MerT Protein Added: ACB72721.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAC44731.1 espC serine protease autotransporter toxin EspC Protein Added: AAC74250.1 ymgB biofilm/acid-resistance regulator AriR Protein Added: AAC76298.1 acrF multidrug efflux RND transporter permease subunit AcrF Protein Added: AAC77293.1 mdtM multidrug efflux MFS transporter MdtM Protein Added: AAL57565.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAB82994.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB82996.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB82998.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB83000.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAB83002.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: BAB83003.1 stx2Bg Shiga toxin Stx2g subunit B Protein Added: BAB83005.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: BAB83007.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: BAB83020.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: BAB83022.1 stx1Ac Shiga toxin Stx1c subunit A Protein Added: BAB83023.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: BAB83024.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: AAL72309.1 sepA serine protease autotransporter toxin SepA Protein Added: AAL72350.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: AAL05407.1 tcrB copper-translocating P-type ATPase TcrB Protein Added: ACD06066.1 capU putative hexosyltransferase CapU Protein Added: ACD06132.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: ACD07996.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: ACD09076.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: BAA11821.1 chrR class I chromate reductase ChrR Protein Added: CAQ45062.1 emrC multidrug efflux transporter outer membrane subunit EmrC Protein Added: CAQ45063.1 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA Protein Added: CAQ45064.1 emrB multidrug efflux MFS transporter permease subunit EmrB Protein Added: ACF05260.1 agg4A aggregative adherence fimbria 4 major subunit Agg4A/HdaA Protein Added: ACF30254.1 mtrR multidrug efflux system transcriptional repressor MtrR Protein Added: ACF30256.1 mtrF AbgT family antimetabolite efflux transporter MtrF Protein Added: BAG66379.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAG66729.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: BAG66736.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG59623.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG59674.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: ACG59676.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: ACG59681.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG59730.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: ACG59732.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: ACG59737.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACG76368.1 arsP organoarsenical efflux permease ArsP Protein Added: ACI12150.1 terB tellurium resistance membrane protein TerB Protein Added: BAG76115.1 iss increased serum survival lipoprotein Iss Protein Added: AAA98099.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAS08589.1 nleB2 type III secretion system effector arginine glycosyltransferase NleB2 Protein Added: CAS08990.1 nleA type III secretion system effector NleA Protein Added: CAS10463.1 espC serine protease autotransporter toxin EspC Protein Added: CAS06720.1 eae intimin type gamma Protein Added: CAS06721.1 eae intimin type alpha Protein Added: CAS06723.1 eae intimin type alpha Protein Added: BAA20334.1 merR mercury resistance transcriptional regulator MerR Protein Added: BAA20336.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: BAA20337.1 merA mercury(II) reductase Protein Added: AAM70045.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: CAQ87187.1 iroN siderophore salmochelin receptor IroN Protein Added: CAV00478.1 lpfA long polar fimbria major subunit LpfA Protein Added: CAV00812.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: CAV02025.1 capU putative hexosyltransferase CapU Protein Added: CAQ90194.1 iss increased serum survival lipoprotein Iss Protein Added: CAU95796.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: CAU95824.1 agg3D aggregative adherence fimbria 3 chaperone Agg3D Protein Added: CAQ97644.1 iss increased serum survival lipoprotein Iss Protein Added: CAR01635.1 vactox vacuolating autotransporter toxin Vat Protein Added: CAR09703.2 ireA TonB-dependent siderophore receptor IreA Protein Added: CAR12622.1 iss increased serum survival lipoprotein Iss Protein Added: CAR15326.1 air inverse autotransporter adhesin EaeX/Air Protein Added: CAW30811.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: CAW30815.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: ACL13561.1 copR heavy metal response regulator transcription factor CopR Protein Added: ACL13562.1 copS copper resistance membrane spanning protein CopS Protein Added: ACL51961.1 ehxA enterohemolysin Protein Added: ACL51990.1 toxB toxin B Protein Added: AAM88296.1 agg3C aggregative adherence fimbria 3 usher protein Agg3C Protein Added: AAM88297.1 agg3B aggregative adherence fimbria 3 minor subunit Agg3B Protein Added: AAM88298.1 agg3A aggregative adherence fimbria 3 major subunit Agg3A Protein Added: AAM88299.1 astA heat-stable enterotoxin EAST1 Protein Added: AAM88302.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: BAA14138.2 merC organomercurial transporter MerC Protein Added: AAM88668.1 cueA copper resistance metal-translocating P1-type ATPase CueA Protein Added: AAM90978.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: CAX18553.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: CAX18626.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: CAX18635.1 espF type III secretion system LEE effector EspF Protein Added: CAX18641.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAX18646.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: CAX18721.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAX18726.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ACM67143.1 eae intimin type alpha Protein Added: ACM67145.1 eae intimin type iota Protein Added: ACM67146.1 eae intimin type alpha Protein Added: ACM67148.1 eae intimin type gamma Protein Added: ACM67149.1 eae intimin type gamma Protein Added: ACM67152.1 eae intimin type beta Protein Added: ACM67153.1 eae intimin type lambda Protein Added: ACM67154.1 eae intimin type gamma Protein Added: ACM67155.1 eae intimin type epsilon Protein Added: ACM67156.1 eae intimin type epsilon Protein Added: ACM67157.1 eae intimin type beta Protein Added: ACM67158.1 eae intimin type epsilon Protein Added: ACM67160.1 eae intimin type beta Protein Added: ACM67161.1 eae intimin type beta Protein Added: ACM67162.1 eae intimin type gamma Protein Added: ACM67163.1 eae intimin type rho Protein Added: ACM67164.1 eae intimin type gamma Protein Added: ACM67165.1 eae intimin type gamma Protein Added: ACM67166.1 eae intimin type gamma Protein Added: ACM67167.1 eae intimin type epsilon Protein Added: ACM67168.1 eae intimin type alpha Protein Added: ACM67169.1 eae intimin type gamma Protein Added: ACM67172.1 eae intimin type epsilon Protein Added: ACM67177.1 eae intimin type gamma Protein Added: ACM67178.1 eae intimin type epsilon Protein Added: BAH24012.1 toxB toxin B Protein Added: CAB14520.2 acr3 arsenite efflux transporter Acr3 Protein Added: ACO06752.1 emhB efflux RND transporter permease subunit EmhB Protein Added: AAN03785.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: AAN03786.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: AAN04250.1 dpsA non-specific DNA-binding protein DpsA Protein Added: BAC10987.1 stx1Ac Shiga toxin Stx1c subunit A Protein Added: BAC10988.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: BAC10992.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: CAY54182.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: AAN29240.1 bepD multidrug efflux RND transporter periplasmic adaptor subunit BepD Protein Added: AAN29241.1 bepE multidrug efflux RND transporter permease subunit BepE Protein Added: AAN29871.1 bepC multidrug efflux RND transporter outer membrane subunit BepC Protein Added: AAN33534.1 bepG multidrug efflux RND transporter permease subunit BepG Protein Added: AAN33535.1 bepF multidrug efflux RND transporter periplasmic adaptor subunit BepF Protein Added: CAD48850.1 cdtB cytolethal distending toxin type III/V nuclease subunit CdtB Protein Added: CAC86907.1 merB organomercurial lyase MerB Protein Added: BAH65949.1 iroN siderophore salmochelin receptor IroN Protein Added: BAH72965.1 cdtB cytolethal distending toxin type II nuclease subunit CdtB Protein Added: AAN42986.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: AAN43435.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: AAN44449.1 sigA serine protease autotransporter toxin SigA Protein Added: CAQ68302.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ACS88189.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: AAC45719.1 f17a F17A fimbrial adhesin Protein Added: AAC45722.1 f17g F17G fimbrial adhesin Protein Added: AAN68576.1 mrdH Ni(II)/Co(II) efflux transporter permease subunit MrdH Protein Added: AAN68577.1 mreA metal-sensing transcriptional repressor MreA Protein Added: ACT33468.1 f17a F17A fimbrial adhesin Protein Added: ACT33471.1 f17g F17G fimbrial adhesin Protein Added: ACT72391.1 tccP Tir-cytoskeleton coupling protein TccP Protein Added: CAR47993.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAR48009.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAH86759.1 stx2Af Shiga toxin Stx2f subunit A Protein Added: BAH86760.1 stx2Bf Shiga toxin Stx2f subunit B Protein Added: BAA20338.2 merB organomercurial lyase MerB Protein Added: ACU32684.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: ACU65296.1 merA mercury(II) reductase Protein Added: CAX45702.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAX45706.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: CAX45714.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAX45718.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAX45737.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: CAX45739.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: CAX45746.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: CAX51714.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: AAB82330.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAI25473.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: BAI31154.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: BAI32292.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAI32327.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: BAI32516.1 espI serine protease autotransporter EspI Protein Added: BAI33940.1 etpD variant type II secretion system secretin EtpD Protein Added: BAI36256.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: BAI36790.1 nleA type III secretion system effector NleA Protein Added: BAI37513.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: BAI37519.1 espF type III secretion system LEE effector EspF Protein Added: BAI37525.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: BAA23166.1 merG phenylmercury resistance protein MerG Protein Added: AAN76093.1 iroN siderophore salmochelin receptor IroN Protein Added: AAN77057.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAN77061.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAN77063.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: BAI44131.1 agg5A aggregative adherence fimbria V major subunit Agg5A Protein Added: AAD12176.1 srpB solvent efflux RND transporter permease subunit SrpB Protein Added: AAD12177.1 ttgI solvent efflux RND transporter outer membrane subunit SrpC Protein Added: AAD12178.1 srpA solvent efflux RND transporter periplasmic adaptor subunit SrpA Protein Added: AAN78874.1 vactox vacuolating autotransporter toxin Vat Protein Added: AAN79707.1 iroN siderophore salmochelin receptor IroN Protein Added: AAN80033.1 iss increased serum survival lipoprotein Iss Protein Added: AAN83596.1 ireA TonB-dependent siderophore receptor IreA Protein Added: CAB14519.1 arsC thioredoxin-dependent arsenate reductase Protein Added: AAB91079.1 copB copper-binding protein CopB Protein Added: CAA05105.1 copP copper-binding metallochaperone CopP Protein Added: AAB88410.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: EEZ94110.1 sdeA multidrug efflux RND transporter periplasmic adaptor subunit SdeA Protein Added: AAO17297.1 eatA serine protease autotransporter toxin EatA Protein Added: ADA73787.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: ADA76801.1 sepA serine protease autotransporter toxin SepA Protein Added: AAO19475.1 stx1Ad Shiga toxin Stx1d subunit A Protein Added: AAO19476.1 stx1Bd Shiga toxin Stx1d subunit B Protein Added: ADA79992.1 merT mercuric transport protein MerT Protein Added: CBG87859.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: CBG89712.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAD66214.1 vactox vacuolating autotransporter toxin Vat Protein Added: ADB20445.1 toxB toxin B Protein Added: CBG36837.1 eilA HilA family transcriptional regulator EilA Protein Added: CBG36838.1 air inverse autotransporter adhesin EaeX/Air Protein Added: CBG37385.1 aaiC type VI secretion system protein AaiC/Hcp2 Protein Added: CBG27762.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: CBG27784.1 aafB aggregative adherence fimbria II minor subunit AafB Protein Added: CBG27798.1 aafD aggregative adherence fimbria II chaperone AafD Protein Added: CBG27800.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: CBG27804.1 aggR aggregative adherence transcriptional regulator AggR Protein Added: CBG27807.1 aap dispersin Aap Protein Added: CBG27812.1 aar AggR-activated transcriptional regulator Aar Protein Added: AAD12174.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: AAO49780.1 ttgD toluene efflux RND transporter periplasmic adaptor subunit TtgD Protein Added: AAC38390.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAC38394.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AAC38400.1 espF type III secretion system LEE effector EspF Protein Added: BAA24822.1 arsA arsenite efflux transporter ATPase subunit ArsA Protein Added: AAA20885.1 astA heat-stable enterotoxin EAST1 Protein Added: AAA23736.1 f17g F17G fimbrial adhesin Protein Added: AAA23737.1 f17a F17A fimbrial adhesin Protein Added: ADD58872.1 espF type III secretion system LEE effector EspF Protein Added: ADD58881.1 eae intimin type gamma Protein Added: ADD58883.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: EFF39147.1 norM sodium-coupled multidrug efflux MATE transporter NorM Protein Added: AAO66617.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: BAJ04486.1 perA BFP system transcriptional regulator PerA Protein Added: BAJ04488.1 perA BFP system transcriptional regulator PerA Protein Added: AAC38219.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: AAC38220.1 merA mercury(II) reductase Protein Added: AAC38221.1 merD mercury resistance co-regulator MerD Protein Added: ADE90928.1 vactox vacuolating autotransporter toxin Vat Protein Added: AAC38229.1 merR mercury resistance transcriptional regulator MerR Protein Added: AAC38230.1 merB organomercurial lyase MerB Protein Added: AAC38231.1 merT mercuric transport protein MerT Protein Added: AAC38232.1 merP mercury resistance system periplasmic binding protein MerP Protein Added: AAC38233.1 merC organomercurial transporter MerC Protein Added: AAC38236.1 merE broad-spectrum mercury transporter MerE Protein Added: ADF64798.1 ncrC Ni(II)/Co(II) efflux transporter permease subunit NcrC Protein Added: CBK85583.1 iroN siderophore salmochelin receptor IroN Protein Added: CBL93318.1 capU putative hexosyltransferase CapU Protein Added: CBL93506.1 lngA type IV pilus longus major pilin Protein Added: ADI59685.1 astA heat-stable enterotoxin EAST1 Protein Added: ADI95409.1 ttgE multidrug efflux RND transporter permease subunit TtgE Protein Added: ADI95411.1 ttgT efflux transport transcriptional regulator TtgT Protein Added: AAP03990.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAP18950.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: ADK23698.1 qacR multidrug-binding transcriptional regulator QacR Protein Added: ADK73987.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAM22256.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAM22257.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: CAD56174.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAD56186.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAA16360.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: AAA16361.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: AAA16362.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ADM83435.1 nleA type III secretion system effector NleA Protein Added: ADN71659.1 iss increased serum survival lipoprotein Iss Protein Added: AAP37403.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: AAC26634.1 pet serine protease autotransporter toxin Pet Protein Added: CBJ04488.1 cfaC CFA/I pilus usher protein CfaC Protein Added: AAC15683.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ADO96486.1 hmrM sodium-coupled multidrug efflux MATE transporter HmrM Protein Added: ADP02162.1 merA mercury(II) reductase Protein Added: CAA73506.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: ADR26561.1 iss increased serum survival lipoprotein Iss Protein Added: ADR70747.1 copA laccase-like oxidase CopA Protein Added: ADR70748.1 copB copper-binding protein CopB Protein Added: BAC77251.1 sdeY multidrug efflux RND transporter permease subunit SdeY Protein Added: ADW66881.1 arsH arsenic resistance NADPH-dependent reductase ArsH Protein Added: AAP78989.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: BAC78639.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: BAC78640.1 stx1Ba Shiga toxin Stx1a subunit B Protein Added: AAC69314.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAC69318.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: BAJ79293.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79295.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79296.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79297.1 aafA aggregative adherence fimbria II major subunit AafA Protein Added: BAJ79299.1 agg5A aggregative adherence fimbria V major subunit Agg5A Protein Added: BAJ79300.1 agg5A aggregative adherence fimbria V major subunit Agg5A Protein Added: ADY84088.1 nreB nickel resistance MFS transporter NreB Protein Added: AAC24352.1 ehxA enterohemolysin Protein Added: ADZ45128.1 ehxA enterohemolysin Protein Added: AAP88295.1 copA laccase-like oxidase CopA Protein Added: AEC46567.1 copA laccase-like oxidase CopA Protein Added: AEC46568.1 copB copper-binding protein CopB Protein Added: AAC38671.1 ttgB multidrug efflux RND transporter permease subunit TtgB Protein Added: BAA31774.1 ehxA enterohemolysin Protein Added: BAA31815.1 toxB toxin B Protein Added: BAA31832.1 katP catalase/peroxidase KatP Protein Added: BAA31836.1 espP serine protease autotransporter EspP Protein Added: AAQ17236.1 mco multi-copper oxidase Mco Protein Added: AAQ17546.1 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAA74174.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AEG95593.1 iroN siderophore salmochelin receptor IroN Protein Added: AAQ20107.1 cfaC CFA/I pilus usher protein CfaC Protein Added: AEK01061.1 iroN siderophore salmochelin receptor IroN Protein Added: AAC31499.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAY90617.2 emhA efflux RND transporter periplasmic adaptor subunit EmhA Protein Added: CAA12346.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA12348.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AEM17342.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: AAC33154.1 lngA type IV pilus longus major pilin Protein Added: AEQ14997.1 eilA HilA family transcriptional regulator EilA Protein Added: AEQ15694.1 capU putative hexosyltransferase CapU Protein Added: AAC33908.1 merC organomercurial transporter MerC Protein Added: CCE21264.1 agg3A aggregative adherence fimbria 3 major subunit Agg3A Protein Added: EHE72460.1 pmrA multidrug efflux MFS transporter PmrA Protein Added: EHF16244.1 aatA dispersin export ABC transporter outer membrane protein AatA Protein Added: EHF16297.1 aggB aggregative adherence fimbria I minor subunit AggB Protein Added: EHF16298.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: AET11941.1 nleA type III secretion system effector NleA Protein Added: AET11995.1 nleA type III secretion system effector NleA Protein Added: AET12008.1 nleA type III secretion system effector NleA Protein Added: BAL46940.1 eae intimin type alpha Protein Added: BAL46941.1 eae intimin type epsilon Protein Added: BAL47132.1 eae intimin type epsilon Protein Added: BAL47176.1 eae intimin type rho Protein Added: BAL47179.1 eae intimin type epsilon Protein Added: BAL47181.1 eae intimin type alpha Protein Added: AEZ42789.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AEZ43710.1 nleA type III secretion system effector NleA Protein Added: AAQ92182.1 emhC efflux RND transporter outer membrane subunit EmhC Protein Added: CAA77068.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: AAR02190.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: BAL72684.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: BAL72697.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: AAR12207.1 cdtB cytolethal distending toxin type III/V nuclease subunit CdtB Protein Added: AAC69584.1 ybtQ yersiniabactin ABC transporter ATP-binding/permease protein YbtQ Protein Added: AAR13270.1 iroN siderophore salmochelin receptor IroN Protein Added: AFH14350.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: CAD87828.1 sta1 heat-stable enterotoxin ST-I group a Protein Added: BAA34299.1 mexX multidrug efflux RND transporter periplasmic adaptor subunit MexX Protein Added: AFK88558.1 auto-sat serine protease autotransporter toxin Sat Protein Added: AFM31243.1 tccP Tir-cytoskeleton coupling protein TccP2 Protein Added: AFM70729.1 copA copper-translocating P-type ATPase CopA Protein Added: AFM70730.1 copB copper/silver-translocating P-type ATPase CopB Protein Added: AAC82360.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: AAR82963.1 nirA nickel resistance membrane nickel efflux protein NirA Protein Added: AAR82964.1 nirB nickel-sensing transcriptional repressor NirB Protein Added: AAR82966.1 nirD nickel resistance OB fold protein NirD Protein Added: AFQ65076.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAA50007.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: CAA12345.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA12350.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA12351.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AFS59871.1 sepA serine protease autotransporter toxin SepA Protein Added: AFS85685.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAC99337.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAA21388.1 ybtP yersiniabactin ABC transporter ATP-binding/permease protein YbtP Protein Added: BAA36431.1 merR mercury resistance transcriptional regulator MerR Protein Added: BAA36433.1 merD mercury resistance co-regulator MerD Protein Added: CAA40744.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAA23532.1 ltcA heat-labile enterotoxin LT subunit A Protein Added: CAA32535.1 fim41a fimbrial adhesin F41 protein Fim41a Protein Added: AAD05936.1 copP copper-binding metallochaperone CopP Protein Added: AAS07580.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07581.1 stx2Bc Shiga toxin Stx2c subunit B Protein Added: AAS07582.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07586.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAS07588.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAS07589.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: AAS07590.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07596.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAS07600.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAS07606.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAD11743.1 silE silver-binding protein SilE Protein Added: AAD11746.1 silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC Protein Added: AAD11748.1 silB Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB Protein Added: AAD11749.1 silA Cu(+)/Ag(+) efflux RND transporter permease subunit SilA Protein Added: AAD11750.1 silP Ag(+)-translocating P-type ATPase SilP Protein Added: AFX83959.1 subA subtilase AB5 cytotoxin subunit A Protein Added: AAS21297.1 tbtR tribuytltin resistance regulator TbtR Protein Added: CAA43585.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAD15663.1 tbtA multidrug efflux RND transporter periplasmic adaptor subunit TbtA Protein Added: AAD15664.1 tbtB multidrug efflux RND transporter permease subunit TbtB Protein Added: AAD15665.1 tbtM multidrug efflux RND transporter outer membrane channel subunit TbtM Protein Added: AAD17509.1 f17a F17A fimbrial adhesin Protein Added: AAD17510.1 f17a F17A fimbrial adhesin Protein Added: AAD17511.1 f17a F17A fimbrial adhesin Protein Added: AAD17513.1 f17g F17G fimbrial adhesin Protein Added: AAD17514.1 f17g F17G fimbrial adhesin Protein Added: AAD17515.1 f17g F17G fimbrial adhesin Protein Added: AAA18786.1 cdtB cytolethal distending toxin type II nuclease subunit CdtB Protein Added: CAA77320.1 merR mercury resistance transcriptional regulator MerR Protein Added: CAA77324.1 merD mercury resistance co-regulator MerD Protein Added: CAA77325.1 merE broad-spectrum mercury transporter MerE Protein Added: CAA81047.1 mtrR multidrug efflux system transcriptional repressor MtrR Protein Added: AAA74436.1 mexA multidrug efflux RND transporter periplasmic adaptor subunit MexA Protein Added: AGC14252.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAS47019.1 nleC type III secretion system effector zinc metalloprotease NleC Protein Added: AGC85979.1 iss increased serum survival lipoprotein Iss Protein Added: CCG33322.1 iroN siderophore salmochelin receptor IroN Protein Added: AAS50165.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAO18187.2 sdeB multidrug efflux RND transporter permease subunit SdeB Protein Added: AAA98221.1 merR mercury resistance transcriptional regulator MerR Protein Added: AAS76847.1 fedA F18 fimbrial major subunit FedA Protein Added: AAD25959.1 merR2 mercury resistance transcriptional regulator MerR2 Protein Added: AAA98245.1 merA mercury(II) reductase Protein Added: AAD27810.1 aafC aggregative adherence fimbria II usher protein AafC Protein Added: AAA24698.1 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh Protein Added: CAE82650.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: CAE82653.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: CAE82670.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: AAD28079.1 hlyE hemolysin HlyE Protein Added: CAA83535.1 aggR aggregative adherence transcriptional regulator AggR Protein Added: EMS03085.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: CAE55775.1 auto-sat serine protease autotransporter toxin Sat Protein Added: AAT36311.1 rpeA serine protease autotransporter colonization factor RpeA Protein Added: BAA77749.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: BAA77750.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: BAA77751.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAA46767.1 stx2Ab Shiga toxin Stx2b subunit A Protein Added: CAA46768.1 stx2Bb Shiga toxin Stx2b subunit B Protein Added: CAA77936.1 emrE multidrug efflux SMR transporter EmrE Protein Added: AAT65972.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAT66000.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAT66010.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAT66011.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: AAT66012.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AGL46515.1 merF mercury resistance system transport protein MerF Protein Added: AAT68784.1 subB subtilase AB5 cytotoxin subunit B Protein Added: AAT68785.1 subA subtilase AB5 cytotoxin subunit A Protein Added: AAT76975.1 lpfA long polar fimbria major subunit LpfA-O113 Protein Added: AAD39553.1 ttgA toluene efflux RND transporter periplasmic adaptor subunit TtgA Protein Added: AAU01878.1 sepA serine protease autotransporter toxin SepA Protein Added: AAN38824.2 adeE multidrug efflux RND transporter permease subunit AdeE Protein Added: AAU10477.1 adeD multidrug efflux RND transporter periplasmic adaptor subunit AdeD Protein Added: AAU88208.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAU88264.1 cdtB cytolethal distending toxin nuclease subunit CdtB Protein Added: AAA57451.1 aggD aggregative adherence fimbria I chaperone AggD Protein Added: AAA57452.1 aggC aggregative adherence fimbria I usher protein AggC Protein Added: AAA57453.1 aggB aggregative adherence fimbria I minor subunit AggB Protein Added: AAA57454.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: CAA85366.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAA85368.1 stx1Aa Shiga toxin Stx1a subunit A Protein Added: CAA85370.1 stx1Ac Shiga toxin Stx1c subunit A Protein Added: CAA85371.1 stx1Bc Shiga toxin Stx1c subunit B Protein Added: EQX61716.1 aggA aggregative adherence fimbria I major subunit AggA Protein Added: AAU95470.1 nleB type III secretion system effector arginine glycosyltransferase NleB Protein Added: AAU95768.1 mepA multidrug efflux MATE transporter MepA Protein Added: CAG17536.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: CAG17541.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: AAD43578.1 astA heat-stable enterotoxin EAST1 Protein Added: AAD43579.1 astA heat-stable enterotoxin EAST1 Protein Added: CAA85780.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: AAA80193.1 mtrC multidrug efflux RND transporter periplasmic adaptor subunit MtrC Protein Added: AAD44693.1 mtrA efflux transporter MtrCDE transcriptional activator MtrA Protein Added: AAD47284.1 terZ tellurium resistance-associated protein TerZ Protein Added: AAW38464.1 lmrS multidrug efflux MFS transporter LmrS Protein Added: CAI43856.1 espF type III secretion system LEE effector EspF Protein Added: CAI43860.1 espB type III secretion system LEE translocon pore-forming subunit EspB Protein Added: CAI43862.1 espA type III secretion system LEE translocon filament protein EspA Protein Added: CAI43865.1 eae intimin type epsilon Protein Added: CAI43867.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAD54074.1 farB fatty acid resistance MFS efflux transporter permease subunit FarB Protein Added: BAA84838.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: BAA84859.1 perA BFP system transcriptional regulator PerA Protein Added: AAT35241.2 tsh temperature-sensitive protease autotransporter hemagglutinin Tsh Protein Added: AAF03351.1 espF type III secretion system LEE effector EspF Protein Added: AHW84565.1 aaiC type VI secretion system protein AaiC/Hcp2 Protein Added: AHW84567.1 aaiC type VI secretion system protein AaiC/Hcp2 Protein Added: AAX47728.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAX47729.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAX47730.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAX47731.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: CAA58525.1 pcoA multicopper oxidase PcoA Protein Added: CAA58526.1 pcoB copper-binding protein PcoB Protein Added: CAA58527.1 pcoC copper resistance system metallochaperone PcoC Protein Added: CAA58528.1 pcoD copper resistance inner membrane protein PcoD Protein Added: CAA58529.1 pcoR copper response regulator transcription factor PcoR Protein Added: CAA58530.1 pcoS copper resistance membrane spanning protein PcoS Protein Added: CAA58532.1 pcoE copper resistance system metallochaperone PcoE Protein Added: AAX63244.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAX63245.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAX63259.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAX63270.1 fedF F18 fimbrial adhesin subunit FedF Protein Added: AAY25390.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAY25394.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAY25395.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAF14522.1 mexX multidrug efflux RND transporter periplasmic adaptor subunit MexX Protein Added: CAI91198.1 stx2Ag Shiga toxin Stx2g subunit A Protein Added: AAF16681.1 srpS solvent efflux transporter transcriptional repressor SrpS Protein Added: AAF16682.1 srpR solvent efflux transporter antirepressor SrpR Protein Added: CAA54115.1 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: AAF23359.1 eae intimin type epsilon Protein Added: CAB64953.1 stx2Af Shiga toxin Stx2f subunit A Protein Added: AAY63864.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: AAY63865.1 stx2Bd Shiga toxin Stx2d subunit B Protein Added: CDY80020.1 hsp20 small heat shock protein sHSP20 Protein Added: AAY90615.1 emhC efflux RND transporter outer membrane subunit EmhC Protein Added: KGL71342.1 silF Ag(+)/Cu(+) efflux RND transporter periplasmic metallochaperone SilF Protein Added: AAF40764.1 farB fatty acid resistance MFS efflux transporter permease subunit FarB Protein Added: AAF42063.1 mtrC multidrug efflux RND transporter periplasmic adaptor subunit MtrC Protein Added: AAB26855.2 nfaE Dr family non-fimbrial adhesin I chaperone NfaE Protein Added: CAB82448.1 cnrY nickel resistance system anti-sigma factor CnrY Protein Added: AAZ76497.1 ehxA enterohemolysin Protein Added: AAZ76514.1 espP serine protease autotransporter EspP Protein Added: AAZ76524.1 subA subtilase AB5 cytotoxin subunit A Protein Added: AAZ87985.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: AAZ88030.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: AAZ89804.1 sigA serine protease autotransporter toxin SigA Protein Added: AAZ91108.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: ABA25986.1 merF mercury resistance system transport protein MerF Protein Added: AAX22079.2 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: AAA65102.1 nccX periplasmic metal sensor NccX Protein Added: AAA65103.1 nccH nickel/cobalt/cadmium resistance ECF sigma factor NccH Protein Added: ABB16332.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: ABB36584.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: ABB36586.1 stx2Ad Shiga toxin Stx2d subunit A Protein Added: ABB61187.1 iroN siderophore salmochelin receptor IroN Protein Added: ABB62096.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABB62098.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABB64677.1 ipaD type III secretion system needle tip complex protein IpaD Protein Added: ABB65884.1 ipaH3 T3SS effector E3 ubiquitin-protein ligase IpaH3 Protein Added: ABB66229.1 ipaH9.8 T3SS effector E3 ubiquitin-protein ligase IpaH9.8 Protein Added: ABB68924.1 virF AraC family invasion system transcriptional regulator VirF Protein Added: KLB41245.1 copL transcriptional regulator CopL Protein Added: CAI79539.1 eatA serine protease autotransporter toxin EatA Protein Added: CAJ44959.1 mchF microcin H47 export transporter peptidase/ATP-binding subunit MchF Protein Added: CAB77169.2 stx2Ae Shiga toxin Stx2e subunit A Protein Added: CAB94149.1 stx2Ba Shiga toxin Stx2a subunit B Protein Added: AAC34727.1 faeG F4 fimbrial adhesin subunit FaeG Protein Added: BAA96815.1 tir type III secretion system LEE translocated intimin receptor Tir Protein Added: AAA69514.1 f17g F17G fimbrial adhesin Protein Added: CAA88252.1 sepA serine protease autotransporter toxin SepA Protein Added: BAE79899.1 smfY multidrug efflux MFS transporter SmfY Protein Added: ABE06598.1 sfaS S-fimbrial adhesin minor subunit SfaS Protein Added: ABE10324.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: CAJ34994.1 bfpA bundle-forming pilus major subunit BfpA Protein Added: ABF13034.1 merD mercury resistance co-regulator MerD Protein Added: ABF13067.1 cnrC nickel efflux RND transporter outer membrane subunit CnrC Protein Added: ABF13069.1 cnrA nickel efflux RND transporter permease subunit CnrA Protein Added: ABF13070.1 cnrT nickel diffusion facilitator CnrT Protein Added: ABF14406.1 ncrA Metal Resistance Protein Added: ABF14407.1 ncrB nickel-sensing transcriptional repressor NcrB Protein Added: CAK02719.1 cnf1 cytotoxic necrotizing factor CNF1 Protein Added: CAA90630.1 stx2Aa Shiga toxin Stx2a subunit A Protein Added: BAT41861.1 eae intimin type alpha Protein Added: CAK15125.1 mexE MexE family multidrug efflux RND transporter periplasmic adaptor subunit Protein Added: AAG01033.1 stx2Ac Shiga toxin Stx2c subunit A Protein Added: AAB59153.1 cadC Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory transcriptional repressor CadC Protein Added: ABF61434.1 ncrA Metal Resistance Protein Added: ABF61435.1 ncrB nickel-sensing transcriptional repressor NcrB Protein Added: ABF61437.1 ncrY nickel resistance OB fold protein NcrY Protein Added: AAG05881.1 mexE MexE family multidrug efflux RND transporter periplasmic adaptor subunit Protein Added: AAG10695.1 perA BFP system transcriptional regulator PerA Protein Added: WP_000697899.1 pmrA pmrA Protein Added: WP_097509477.1 acrB acrB - AMRFinder HMM library Changes: Prev. Release: 574 This Release: 610 Removed: 2 Added: 38 Changed: 572 HMM Removed: NF000478.2 linco_LnuE HMM Removed: NF012180.1 tet_MFS_43 HMM Added: NF000131.1 MATE_multi_MepA HMM Added: NF000249.1 MexE HMM Added: NF000252.1 MexX HMM Added: NF000263.1 MATE_multi_NorM HMM Added: NF000282.2 RND_permease_1 HMM Added: NF000314.1 adeB HMM Added: NF000315.1 adeC-adeK-oprM HMM Added: NF000336.1 emrE HMM Added: NF007842.1 PRK10555.1 HMM Added: NF010310.2 PRK13747.1 HMM Added: NF010315.0 PRK13752.1 HMM Added: NF011706.2 PRK15127.1 HMM Added: NF028537.1 P_eth_NH2_trans HMM Added: NF033086.2 penta_rpt_Qnr HMM Added: NF033134.0 cmlA_floR HMM Added: NF033142.1 efflux_OM_AdeC HMM Added: NF033143.1 efflux_OM_AdeK HMM Added: NF033555.1 lyase_MerB HMM Added: NF033560.1 merT_RC607 HMM Added: NF033565.0 trans_MerF HMM Added: NF033627.3 intimin_all HMM Added: NF033637.1 transloc_TIR HMM Added: NF033639.1 intimin_alpha HMM Added: NF033643.1 EspJ_gen HMM Added: NF033646.1 toxin_EAST1 HMM Added: NF033651.1 cyto_nec_fctrs HMM Added: NF033658.1 Shiga_Stx1A HMM Added: NF033659.0 Shiga_Stx1B HMM Added: NF033660.0 Shiga_Stx2B HMM Added: NF033661.1 Shiga_Stx2A HMM Added: NF033727.1 chaperon_ArsD HMM Added: NF033781.1 chaper_CopP HMM Added: NF033783.1 coreg_MerD HMM Added: NF033784.1 transport_merC HMM Added: NF033786.1 phenyl_MerG HMM Added: NF033834.1 RND_adapt_MexA HMM Added: TIGR02052.1 TIGR02052 HMM Added: TIGR02053.1 TIGR02053 --------------------------------------------------------------------- Changes included in 2019-04-29.1 --------------------------------------------------------------------- Summary: In addition to the usual addition of 134 new genes and alleles community feedback led to the renaming of a few dfr genes. The family heirarchy file (fam.tab) was cleaned up by removing a number of superfluous entries. Changes included in 2019-04-29.1 - Protein changes: Prev. Release: 4810 This Release: 4942 Removed: 1 Added: 134 Modified: 3 Protein Removed: WP_109545040.1 chrB Protein Added: WP_000054744.1 satA_Ba Protein Added: WP_001211209.1 blaADC-140 Protein Added: WP_001211210.1 blaADC-185 Protein Added: WP_001211214.1 blaADC-144 Protein Added: WP_001211215.1 blaADC-115 Protein Added: WP_001572373.1 mcr-9.1 Protein Added: WP_002126587.1 blaADC-120 Protein Added: WP_002157727.1 blaADC-117 Protein Added: WP_003112187.1 blaADC-191 Protein Added: WP_003242546.1 satA_Bs Protein Added: WP_004643536.1 blaADC-128 Protein Added: WP_004700205.1 blaADC-133 Protein Added: WP_004707701.1 blaADC-131 Protein Added: WP_004712857.1 blaADC-119 Protein Added: WP_004790939.1 blaADC-135 Protein Added: WP_004840559.1 blaADC-123 Protein Added: WP_004886093.1 blaADC-130 Protein Added: WP_005039111.1 blaADC-129 Protein Added: WP_005046018.1 blaADC-127 Protein Added: WP_005068074.1 blaADC-132 Protein Added: WP_005109685.1 blaADC-121 Protein Added: WP_005123276.1 blaADC-122 Protein Added: WP_005131186.1 blaADC-125 Protein Added: WP_005307218.1 blaADC-134 Protein Added: WP_005404206.1 blaOXA-813 Protein Added: WP_005405613.1 blaOXA-814 Protein Added: WP_013197184.1 blaADC-193 Protein Added: WP_014207272.1 blaADC-149 Protein Added: WP_016137488.1 blaADC-136 Protein Added: WP_016140427.1 blaADC-137 Protein Added: WP_016146025.1 blaADC-138 Protein Added: WP_017386568.1 blaADC-150 Protein Added: WP_017778762.1 mcr-3.27 Protein Added: WP_017816757.1 blaADC-116 Protein Added: WP_026382828.1 blaOXA-114i Protein Added: WP_026444036.1 blaOXA-816 Protein Added: WP_032039838.1 blaADC-139 Protein Added: WP_032053762.1 blaOXA-819 Protein Added: WP_032057042.1 blaOXA-820 Protein Added: WP_032062810.1 blaADC-141 Protein Added: WP_032625176.1 blaACT-66 Protein Added: WP_033502167.1 blaADC-143 Protein Added: WP_034670108.1 blaOXA-818 Protein Added: WP_034688190.1 blaOXA-812 Protein Added: WP_036299413.1 sulR Protein Added: WP_039246976.1 blaADC-148 Protein Added: WP_039258389.1 blaADC-146 Protein Added: WP_039270258.1 blaADC-145 Protein Added: WP_044718369.1 blaADC-147 Protein Added: WP_047726486.1 blaACT-65 Protein Added: WP_053498400.1 blaOXA-114h Protein Added: WP_054437016.1 blaOXA-114j Protein Added: WP_054471662.1 blaOXA-114m Protein Added: WP_054500785.1 blaOXA-789 Protein Added: WP_054517040.1 blaOXA-114l Protein Added: WP_057061999.1 blaOXA-821 Protein Added: WP_059247009.1 blaADC-184 Protein Added: WP_063099318.1 blaADC-151 Protein Added: WP_063147148.1 blaACT-67 Protein Added: WP_072292271.1 blaADC-186 Protein Added: WP_075040046.1 blaOXA-817 Protein Added: WP_076412384.1 blaOXA-114p Protein Added: WP_099595307.1 dfrA35 Protein Added: WP_103663397.1 sulX Protein Added: WP_106743337.1 mcr-1.18 Protein Added: WP_109545052.1 mcr-1.14 Protein Added: WP_110612827.1 blaOXA-796 Protein Added: WP_111280830.1 blaOXA-815 Protein Added: WP_115470049.1 blaKPC-40 Protein Added: WP_117664257.1 cfxA6 Protein Added: WP_125052776.1 blaADC-114 Protein Added: WP_136512051.1 blaACT-68 Protein Added: WP_136512052.1 blaADC-109 Protein Added: WP_136512053.1 blaADC-110 Protein Added: WP_136512054.1 blaADC-112 Protein Added: WP_136512055.1 blaADC-113 Protein Added: WP_136512056.1 blaADC-187 Protein Added: WP_136512057.1 blaADC-188 Protein Added: WP_136512058.1 blaADC-189 Protein Added: WP_136512059.1 blaADC-190 Protein Added: WP_136512060.1 blaADC-192 Protein Added: WP_136512061.1 blaADC-24 Protein Added: WP_136512062.1 blaADC-65 Protein Added: WP_136512063.1 blaADC-66 Protein Added: WP_136512064.1 blaCTX-M-225 Protein Added: WP_136512065.1 blaCTX-M-226 Protein Added: WP_136512066.1 blaFRI-7 Protein Added: WP_136512067.1 blaIMI-18 Protein Added: WP_136512068.1 blaIMP-39 Protein Added: WP_136512069.1 blaIMP-46 Protein Added: WP_136512070.1 blaKPC-42 Protein Added: WP_136512071.1 blaKPC-43 Protein Added: WP_136512072.1 blaNDM-28 Protein Added: WP_136512073.1 blaOXA-114k Protein Added: WP_136512074.1 blaOXA-114n Protein Added: WP_136512075.1 blaOXA-114q Protein Added: WP_136512076.1 blaOXA-114r Protein Added: WP_136512077.1 blaOXA-114s Protein Added: WP_136512078.1 blaOXA-114t Protein Added: WP_136512079.1 blaOXA-114u Protein Added: WP_136512080.1 blaOXA-114v Protein Added: WP_136512081.1 blaOXA-114w Protein Added: WP_136512082.1 blaOXA-114x Protein Added: WP_136512083.1 blaOXA-787 Protein Added: WP_136512084.1 blaOXA-788 Protein Added: WP_136512085.1 blaOXA-793 Protein Added: WP_136512086.1 blaOXA-794 Protein Added: WP_136512087.1 blaOXA-795 Protein Added: WP_136512088.1 blaOXA-797 Protein Added: WP_136512089.1 blaOXA-798 Protein Added: WP_136512090.1 blaOXA-799 Protein Added: WP_136512091.1 blaOXA-800 Protein Added: WP_136512092.1 blaOXA-801 Protein Added: WP_136512093.1 blaOXA-802 Protein Added: WP_136512094.1 blaOXA-803 Protein Added: WP_136512095.1 blaOXA-804 Protein Added: WP_136512096.1 blaOXA-805 Protein Added: WP_136512097.1 blaOXA-806 Protein Added: WP_136512098.1 blaOXA-807 Protein Added: WP_136512099.1 blaOXA-808 Protein Added: WP_136512100.1 blaOXA-809 Protein Added: WP_136512101.1 blaOXA-810 Protein Added: WP_136512102.1 blaOXA-811 Protein Added: WP_136512103.1 blaOXA-823 Protein Added: WP_136512104.1 blaOXA-824 Protein Added: WP_136512105.1 blaPER-13 Protein Added: WP_136512106.1 blaVIM-48 Protein Added: WP_136512107.1 blaVIM-55 Protein Added: WP_136512108.1 blaVIM-63 Protein Added: WP_136512109.1 blaVIM-66 Protein Added: WP_136512110.1 mcr-1.16 Protein Added: WP_136512111.1 mcr-1.17 Protein Added: WP_136512112.1 mcr-3.29 Protein Modified: WP_001031075.1 dfr18 updated to WP_001031075.1 dfrA18 Protein Modified: WP_032490189.1 dfrA18 updated to WP_032490189.1 dfrA19 Protein Modified: WP_063843245.1 chrB updated to WP_063843245.1 chrB_rRNA_meth - AMR HMM library Changes: Prev. Release: 571 This Release: 574 Removed: 0 Added: 3 Changed: 571 HMM Added: NF033818.0 blaOXA-114_like HMM Added: NF033836.1 polymyxin_MCR9 HMM Added: NF033851.1 trim_DfrA35 HMM Modified: NF000039.1 trim_Dfr18 renamed to NF000039.1 trim_DfrA18 HMM Modified: NF000041.1 trim_DfrA18_A19 renamed to NF000041.1 trim_DfrA19 HMM Modified: NF000422.2 blaPDC updated to NF000422.6 blaPDC - Protein family changes: Prev. Release: 1177 This Release: 1119 Removed: 68 Added: 10 Modified: 4 Family Removed: - PORIN Family Removed: - aac(1) Family Removed: - aac(3')-IIe Family Removed: - aac(3)-Ie Family Removed: - aac(3)-VI Family Removed: - aac(3)-Vb Family Removed: - aac(6')-Ib8 Family Removed: - aacA44 Family Removed: - aadA1bt Family Removed: - aadA1r Family Removed: - aadA24 Family Removed: - ampC_Eae Family Removed: - ampH Family Removed: - ampS Family Removed: - ant(3'')(9) Family Removed: - ant(3'')-Ii Family Removed: - aph(3')-Ic Family Removed: - arr-Cb Family Removed: - blaCMG Family Removed: - blaKLUG Family Removed: - blaLMB Family Removed: - blaMSI-OXA Family Removed: - blaOXA_missing Family Removed: - blaPNGM Family Removed: - blaZEG Family Removed: - blmS Family Removed: - catA12 Family Removed: - ccrA Family Removed: NF000488.1 chrB Family Removed: - cml Family Removed: - cmlA7 Family Removed: - cmlA9 Family Removed: NF000039.1 dfr18 Family Removed: NF000041.1 dfrA18_dfrA19 Family Removed: - dfrA1_var Family Removed: - dfrA29 Family Removed: - dfrA33 Family Removed: - dfrB7 Family Removed: - flo Family Removed: - mef(E) Family Removed: - mef(G) Family Removed: - mef(I) Family Removed: - mph(D) Family Removed: - nimF Family Removed: - nimH Family Removed: - omp35 Family Removed: - ompE35 Family Removed: - otr(C) Family Removed: - penA Family Removed: - sat2A Family Removed: - sat3A Family Removed: - spc Family Removed: - sul1delta Family Removed: - vanH-Ac2 Family Removed: - vanH-F Family Removed: - vanR-Pt Family Removed: - vanR-Pt2 Family Removed: - vanS-I Family Removed: - vanSc Family Removed: - vanTc4 Family Removed: - vanX-Ac2 Family Removed: - vanX-F Family Removed: - vanX-Pt2 Family Removed: - vanY-40021673 Family Removed: - vanY-D4 Family Removed: - vanY-D5 Family Removed: - vanY-M Family Removed: - vanY-Pt2 Family Added: NF033818.0 blaOXA-114_like Family Added: NF033851.1 dfrA35 Family Added: NF033124.1 estX Family Added: NF033836.1 mcr-9 Family Added: - satA_Bs Family Added: - sulR Family Added: - sulX Family Changed: NF000422.2 blaPDC updated to NF000422.6 blaPDC Family Changed: NF000488.1 chrB renamed to chrB_rRNA_meth Family Changed: NF000039.1 dfr18 renamed to dfrA18 Family Changed: NF000041.1 dfrA18_dfrA19 renamed to dfrA19 --------------------------------------------------------------------- Changes included in 2019-02-08.1 --------------------------------------------------------------------- Two incorrectly assigned proteins were accidentally released. They are not AMR proteins and should not have been released. This release simply removes them and is otherwise unchanged. - Protein changes: Prev. Release: 4812 This Release: 4810 Removed: 2 Added: 0 Changed: 4810 Protein Removed: WP_000122253.1 sat Protein Removed: WP_001045652.1 sat --------------------------------------------------------------------- Changes included in 2019-02-04.1 --------------------------------------------------------------------- - Protein name changes: "inhibitor-resistant" was added to the names of: blaKPC-8 blaKPC-30 blaKPC-31 blaKPC-32 blaKPC-33 - Protein changes: Prev. Release: 4730 This Release: 4812 Removed: 0 Added: 82 Protein modified: WP_063855700.1 tet(35) replaced with WP_005480402.1 Protein Added: WP_000122253.1 sat Protein Added: WP_001045652.1 sat Protein Added: WP_002415638.1 poxtA Protein Added: WP_003234144.1 vmlR Protein Added: WP_029728367.1 blaB Protein Added: WP_044103626.1 blaVEB-21 Protein Added: WP_046693238.1 blaADC-181 Protein Added: WP_049637206.1 blaOXA-780 Protein Added: WP_057691114.1 blaADC-182 Protein Added: WP_058492019.1 vanI Protein Added: WP_065980086.1 blaOXA-784 Protein Added: WP_069953510.1 blaAFM-1 Protein Added: WP_069996660.1 mecC3 Protein Added: WP_071223118.1 taeA Protein Added: WP_087343787.1 ant(6)-Ic Protein Added: WP_087344360.1 blaBBI Protein Added: WP_087344902.1 catV Protein Added: WP_087346196.1 ant(4')-Ic Protein Added: WP_087347987.1 rphC Protein Added: WP_087348261.1 rphD Protein Added: WP_087349244.1 mphJ Protein Added: WP_087349651.1 aac(6')-35 Protein Added: WP_114225343.1 blaOXA-739 Protein Added: WP_123002100.1 blaGES-40 Protein Added: WP_123002101.1 blaKPC-38 Protein Added: WP_123002102.1 blaNDM-27 Protein Added: WP_123002103.1 blaVIM-61 Protein Added: WP_126205827.1 blaOXA-785 Protein Added: WP_127728991.1 blaFRI-6 Protein Added: WP_128268231.1 mecC2 Protein Added: WP_128268232.1 blaADC-183 Protein Added: WP_128268233.1 blaCARB-50 Protein Added: WP_128268234.1 blaCFE-2 Protein Added: WP_128268235.1 blaCTX-M-215 Protein Added: WP_128268236.1 blaDHA-28 Protein Added: WP_128268237.1 blaKPC-39 Protein Added: WP_128268238.1 blaOXA-738 Protein Added: WP_128268239.1 blaOXA-740 Protein Added: WP_128268240.1 blaOXA-741 Protein Added: WP_128268241.1 blaOXA-742 Protein Added: WP_128268242.1 blaOXA-743 Protein Added: WP_128268243.1 blaOXA-744 Protein Added: WP_128268244.1 blaOXA-745 Protein Added: WP_128268245.1 blaOXA-746 Protein Added: WP_128268246.1 blaOXA-747 Protein Added: WP_128268247.1 blaOXA-748 Protein Added: WP_128268248.1 blaOXA-749 Protein Added: WP_128268249.1 blaOXA-750 Protein Added: WP_128268250.1 blaOXA-751 Protein Added: WP_128268251.1 blaOXA-752 Protein Added: WP_128268252.1 blaOXA-753 Protein Added: WP_128268253.1 blaOXA-754 Protein Added: WP_128268254.1 blaOXA-755 Protein Added: WP_128268255.1 blaOXA-756 Protein Added: WP_128268256.1 blaOXA-757 Protein Added: WP_128268257.1 blaOXA-758 Protein Added: WP_128268258.1 blaOXA-759 Protein Added: WP_128268259.1 blaOXA-760 Protein Added: WP_128268260.1 blaOXA-761 Protein Added: WP_128268261.1 blaOXA-762 Protein Added: WP_128268262.1 blaOXA-763 Protein Added: WP_128268263.1 blaOXA-764 Protein Added: WP_128268264.1 blaOXA-765 Protein Added: WP_128268265.1 blaOXA-766 Protein Added: WP_128268266.1 blaOXA-767 Protein Added: WP_128268267.1 blaOXA-768 Protein Added: WP_128268268.1 blaOXA-769 Protein Added: WP_128268269.1 blaOXA-770 Protein Added: WP_128268270.1 blaOXA-771 Protein Added: WP_128268271.1 blaOXA-772 Protein Added: WP_128268272.1 blaOXA-773 Protein Added: WP_128268273.1 blaOXA-774 Protein Added: WP_128268274.1 blaOXA-775 Protein Added: WP_128268275.1 blaOXA-776 Protein Added: WP_128268276.1 blaOXA-781 Protein Added: WP_128268277.1 blaOXA-782 Protein Added: WP_128268278.1 blaOXA-783 Protein Added: WP_128268279.1 blaOXA-786 Protein Added: WP_128268280.1 blaPDC-317 Protein Added: WP_128268286.1 blaVEB-20 Protein Added: WP_128268287.1 blaVIM-62 Protein Added: WP_128268288.1 qnrS15 - AMR HMM library Changes: Prev. Release: 568 This Release: 571 Removed: 0 Added: 3 HMM Added: NF033714.1 blaBBI HMM Added: NF033736.1 blaAFM HMM Added: NF033815.0 blaOXA-364_like HMM Modified: NF000355.2 ribo_prot_ABC_F updated to NF000355.3 ribo_prot_ABC_F - Protein family changes: Prev. Release: 1161 This Release: 1177 Removed: 0 Added: 16 Family Added: - aac(6')-35 Family Added: - ant(4')-Ic Family Added: - ant(6)-Ic Family Added: NF033736.1 blaAFM Family Added: NF033714.1 blaBBI Family Added: NF033815.0 blaOXA-364_like Family Added: - mecC2 Family Added: - mecC3 Family Added: - mphJ Family Added: - poxtA Family Added: - rphC Family Added: - rphD Family Added: - rph_gen Family Added: - satA_Ba Family Added: - taeA Family Added: - vmlR Family Changed: NF000355.2 abc-f updated to NF000355.3 abc-f --------------------------------------------------------------------- Changes included in 2018-11-07.1 --------------------------------------------------------------------- Due to a communication error three blaOXA alleles in the AMR database have been reassigned. Alleles published by Tian, et al. (PMID:30247543) have replaced them. AFY12006.1 JX846494.1 WP_072678505.1 NG_061615.1 were blaOXA-669, now they are blaOXA-732 AAL47570.1 AY066004.1 WP_114699266.1 NG_061383.1 were blaOXA-666, now they are blaOXA-729 AXH06203.1 MH684781.1 WP_116786836.1 NG_061623.1 were blaOXA-667, now they are blaOXA-730 - Protein changes: Prev. Release: 4579 This Release: 4730 Removed: 0 Added: 151 Protein Added: WP_004143591.1 blaSHV-206 Protein Added: WP_004384957.1 blaCSA-2 Protein Added: WP_007888761.1 blaCSA-1 Protein Added: WP_011245929.1 clbB Protein Added: WP_011707905.1 blaOXA-725 Protein Added: WP_012116915.1 clbA Protein Added: WP_015892743.1 clbC Protein Added: WP_016162389.1 blaOXA-673 Protein Added: WP_016168805.1 blaOXA-664 Protein Added: WP_016651348.1 blaOXA-670 Protein Added: WP_016657654.1 blaOXA-665 Protein Added: WP_016660101.1 blaOXA-671 Protein Added: WP_016685888.1 blaOXA-715 Protein Added: WP_017822040.1 qnrVC10 Protein Added: WP_023271137.1 blaOXA-672 Protein Added: WP_023341517.1 blaSHV-211 Protein Added: WP_031998610.1 blaOXA-716 Protein Added: WP_032018141.1 blaOXA-717 Protein Added: WP_032495491.1 blaKLUC-3 Protein Added: WP_032495492.1 blaKLUC-4 Protein Added: WP_032974004.1 blaCMA-1 Protein Added: WP_033179079.1 crpP Protein Added: WP_034612711.1 blaOXA-668 Protein Added: WP_056517622.1 blaOXA-669 Protein Added: WP_057097547.1 aph(2'')-If2 Protein Added: WP_058652112.1 dfrA34 Protein Added: WP_064733493.1 blaSHV-207 Protein Added: WP_064760451.1 qepA4 Protein Added: WP_064768701.1 qepA7 Protein Added: WP_077096319.1 blaOXA-724 Protein Added: WP_081406929.1 blaOXA-674 Protein Added: WP_081853183.1 blaELM-1 Protein Added: WP_092689909.1 blaOXA-666 Protein Added: WP_094166899.1 blaCTX-M-224 Protein Added: WP_096735335.1 blaOXA-667 Protein Added: WP_096941464.1 qepA6 Protein Added: WP_100663667.1 blaKLUC-5 Protein Added: WP_101150415.1 blaOXA-726 Protein Added: WP_104159136.1 blaSHV-224 Protein Added: WP_105620838.1 blaCMA-2 Protein Added: WP_109232473.1 blaSHV-220 Protein Added: WP_109638756.1 qepA8 Protein Added: WP_112021705.1 qepA9 Protein Added: WP_113334341.1 qepA10 Protein Added: WP_115196748.1 blaSHV-210 Protein Added: WP_117241614.1 blaSHV-223 Protein Added: WP_122630822.1 blaEFM-1 Protein Added: WP_122630823.1 blaEVM-1 Protein Added: WP_122630824.1 blaECM-1 Protein Added: WP_122630825.1 blaEAM-1 Protein Added: WP_122630826.1 blaGES-38 Protein Added: WP_122630827.1 blaGES-39 Protein Added: WP_122630828.1 blaVIM-53 Protein Added: WP_122630829.1 blaDHT2-1 Protein Added: WP_122630830.1 blaSPN79-1 Protein Added: WP_122630831.1 blaCRD3-1 Protein Added: WP_122630832.1 blaALG6-1 Protein Added: WP_122630833.1 blaALG11-1 Protein Added: WP_122630834.1 blaGRD33-1 Protein Added: WP_122630835.1 blaGRD23-1 Protein Added: WP_122630836.1 blaCMY-158 Protein Added: WP_122630837.1 blaCMY-159 Protein Added: WP_122630838.1 blaSHV-201 Protein Added: WP_122630839.1 blaSHV-202 Protein Added: WP_122630840.1 aph(2'') Protein Added: WP_122630841.1 blaTEM-237 Protein Added: WP_122630842.1 blaOXA-655 Protein Added: WP_122630843.1 blaOXA-656 Protein Added: WP_122630844.1 blaOXA-733 Protein Added: WP_122630845.1 blaPDC-307 Protein Added: WP_122630846.1 blaPDC-308 Protein Added: WP_122630847.1 blaPDC-309 Protein Added: WP_122630848.1 blaPDC-310 Protein Added: WP_122630849.1 blaPDC-311 Protein Added: WP_122630850.1 blaPDC-312 Protein Added: WP_122630851.1 blaPDC-313 Protein Added: WP_122630852.1 blaPDC-314 Protein Added: WP_122630853.1 blaOXA-734 Protein Added: WP_122630854.1 blaOXA-735 Protein Added: WP_122630855.1 blaOXA-736 Protein Added: WP_122630856.1 blaOXA-737 Protein Added: WP_122630857.1 blaOXA-675 Protein Added: WP_122630858.1 blaOXA-676 Protein Added: WP_122630859.1 blaOXA-677 Protein Added: WP_122630860.1 blaOXA-678 Protein Added: WP_122630861.1 blaIMP-80 Protein Added: WP_122630862.1 blaCTX-M-223 Protein Added: WP_122630863.1 blaSHV-205 Protein Added: WP_122630864.1 blaOXA-680 Protein Added: WP_122630865.1 blaSHV-208 Protein Added: WP_122630866.1 blaSHV-209 Protein Added: WP_122630867.1 blaSHV-212 Protein Added: WP_122630868.1 blaSHV-213 Protein Added: WP_122630869.1 blaSHV-214 Protein Added: WP_122630870.1 blaSHV-215 Protein Added: WP_122630871.1 blaSHV-216 Protein Added: WP_122630872.1 blaSHV-217 Protein Added: WP_122630873.1 blaSHV-218 Protein Added: WP_122630874.1 blaSHV-219 Protein Added: WP_122630875.1 blaSHV-221 Protein Added: WP_122630876.1 blaSHV-222 Protein Added: WP_122630877.1 blaSHV-225 Protein Added: WP_122630878.1 blaSHV-226 Protein Added: WP_122630879.1 blaSHV-227 Protein Added: WP_122630880.1 blaSHV-228 Protein Added: WP_122630881.1 blaOXA-681 Protein Added: WP_122630882.1 blaPDC-315 Protein Added: WP_122630883.1 blaPDC-316 Protein Added: WP_122630884.1 blaOXA-682 Protein Added: WP_122630885.1 blaOXA-683 Protein Added: WP_122630886.1 blaOXA-684 Protein Added: WP_122630887.1 blaOXA-685 Protein Added: WP_122630888.1 blaOXA-686 Protein Added: WP_122630889.1 blaOXA-687 Protein Added: WP_122630890.1 blaOXA-688 Protein Added: WP_122630891.1 blaOXA-689 Protein Added: WP_122630892.1 blaOXA-690 Protein Added: WP_122630893.1 blaOXA-691 Protein Added: WP_122630894.1 blaOXA-692 Protein Added: WP_122630895.1 blaOXA-693 Protein Added: WP_122630896.1 blaOXA-694 Protein Added: WP_122630897.1 blaOXA-695 Protein Added: WP_122630898.1 blaOXA-696 Protein Added: WP_122630899.1 blaOXA-697 Protein Added: WP_122630900.1 blaOXA-698 Protein Added: WP_122630901.1 blaOXA-699 Protein Added: WP_122630902.1 blaOXA-700 Protein Added: WP_122630903.1 blaOXA-701 Protein Added: WP_122630904.1 blaOXA-702 Protein Added: WP_122630905.1 blaOXA-703 Protein Added: WP_122630906.1 blaOXA-704 Protein Added: WP_122630907.1 blaOXA-705 Protein Added: WP_122630908.1 blaOXA-706 Protein Added: WP_122630909.1 blaOXA-707 Protein Added: WP_122630910.1 blaOXA-718 Protein Added: WP_122630911.1 blaOXA-719 Protein Added: WP_122630912.1 blaOXA-720 Protein Added: WP_122630913.1 blaOXA-721 Protein Added: WP_122630914.1 blaOXA-722 Protein Added: WP_122630915.1 blaOXA-723 Protein Added: WP_122630916.1 blaOXA-708 Protein Added: WP_122630917.1 blaOXA-709 Protein Added: WP_122630918.1 blaOXA-710 Protein Added: WP_122630919.1 blaOXA-711 Protein Added: WP_122630920.1 blaOXA-712 Protein Added: WP_122630921.1 blaOXA-713 Protein Added: WP_122630922.1 blaOXA-714 Protein Added: WP_122630923.1 blaOXA-777 Protein Added: WP_122630924.1 blaOXA-778 Protein Added: WP_122634438.1 blaOXA-779 Protein Added: WP_122634439.1 blaOXA-679 Gene Symbol Modified: WP_010890145.1 qacE_gen updated to WP_010890145.1 qacE Gene Symbol Modified: WP_053515552.1 qacE_gen updated to WP_053515552.1 qacE Gene Symbol Modified: WP_063844281.1 cphA updated to WP_063844281.1 cphA3 Gene Symbol Modified: WP_063854778.1 qepA updated to WP_063854778.1 qepA5 Gene Symbol Modified: WP_072678505.1 blaOXA-669 updated to WP_072678505.1 blaOXA-732 Gene Symbol Modified: WP_114699266.1 blaOXA-666 updated to WP_114699266.1 blaOXA-729 Gene Symbol Modified: WP_116786836.1 blaOXA-667 updated to WP_116786836.1 blaOXA-730 - AMR HMM library Changes: Prev. Release: 563 This Release: 568 Removed: 0 Added: 5 HMM Added: NF033692.1 APH_2pp_I_a_f_h HMM Added: NF033693.0 AAC_6p_Ie_fam HMM Added: NF033698.1 blaCSA HMM Added: NF033700.1 blaCMA HMM Added: NF033702.0 blaOXA-12_like HMM Name Modified: NF033666.1 blaOXA-664_like updated to NF033666.1 blaOXA-727_like - Protein family changes: Prev. Release: 1133 This Release: 1161 Removed: 0 Added: 28 Family Added: - aac(6')-Ie2 Family Added: NF033693.0 aac(6')-Ie_fam Family Added: NF011706.2 acrB Family Added: NF007842.1 acrD Family Added: NF000314.1 adeB/adeJ Family Added: NF033692.1 aph(2'')-I_a_f_h Family Added: - aph(2'')-If2 Family Added: - blaALG11 Family Added: - blaALG6 Family Added: NF033700.1 blaCMA Family Added: - blaCRD3 Family Added: NF033698.1 blaCSA Family Added: - blaCrA Family Added: - blaDHT2 Family Added: - blaEAM Family Added: - blaECM Family Added: - blaEFM Family Added: - blaELM Family Added: - blaEVM Family Added: - blaGRD23 Family Added: - blaGRD33 Family Added: NF033702.0 blaOXA-12_like Family Added: - blaPNGM Family Added: - blaSPN79 Family Added: - catV Family Added: - crpP Family Added: - dfrA34 Family Added: - qacE Family Renamed: NF033666.1 blaOXA-664_like became blaOXA-727_like --------------------------------------------------------------------- Changes included in 2018-09-14.1 ---------------------------------------------------------------------- - Protein changes: Prev. Release: 4569 This Release: 4579 Removed: 0 Added: 10 Protein Added: WP_116786828.1 mcr-4.6 Protein Added: WP_116786829.1 blaCTX-M-222 Protein Added: WP_116786830.1 mcr-1.15 Protein Added: WP_116786831.1 blaTEM-236 Protein Added: WP_116786832.1 blaKPC-37 Protein Added: WP_116786834.1 blaPDC-304 Protein Added: WP_116786836.1 blaOXA-667 Protein Added: WP_116786837.1 blaPDC-305 Protein Added: WP_116786838.1 blaPDC-306 Protein Added: WP_116786839.1 blaIMP-79 - AMR HMM library Changes: Prev. Release: 563 This Release: 563 Removed: 0 Added: 0 - Protein family changes: Prev. Release: 1133 This Release: 1133 Removed: 0 Added: 0 --------------------------------------------------------------------- Changes included in 2018-08-24.1 --------------------------------------------------------------------- - Protein changes: Prev. Release: 4563 This Release: 4569 Removed: 1 Added: 7 Protein Removed: WP_063843217.1 catA1 Protein Added: WP_003436401.1 vanR-Cd Protein Added: WP_009889012.1 vanZ1 Protein Added: WP_011861275.1 vanS-Cd Protein Added: WP_011861276.1 vanG-Cd Protein Added: WP_020924773.1 blaAXC-1 Protein Added: WP_072310976.1 mcr-8.2 Protein Added: WP_072678505.1 blaOXA-669 - AMR HMM library Changes: Prev. Release: 563 This Release: 563 Removed: 0 Added: 0 - Protein family changes: Prev. Release: 1128 This Release: 1133 Removed: 0 Added: 5 Family Added: - blaAXC Family Added: - vanG-Cd Family Added: - vanR-Cd Family Added: - vanS-Cd Family Added: - vanZ1 --------------------------------------------------------------------- Changes included in 2018-08-01.1 --------------------------------------------------------------------- - Protein changes: Prev. Release: 4528 This Release: 4563 Removed: 0 Added: 35 Protein Added: WP_000622776.1 qacA Protein Added: WP_001159761.1 blaADC-176 Protein Added: WP_001211208.1 blaADC-175 Protein Added: WP_010730188.1 qacZ Protein Added: WP_013095270.1 blaCMH-4 Protein Added: WP_032410229.1 blaOXA-663 Protein Added: WP_033487869.1 blaACT-56 Protein Added: WP_046887417.1 blaCMH-5 Protein Added: WP_047052637.1 blaACT-55 Protein Added: WP_050861789.1 blaACT-64 Protein Added: WP_070210118.1 blaOXA-658 Protein Added: WP_094935119.1 blaACT-57 Protein Added: WP_111772163.1 blaVIM-58 Protein Added: WP_111976052.1 blaACT-60 Protein Added: WP_112017656.1 blaACT-61 Protein Added: WP_112792421.1 blaACT-59 Protein Added: WP_114699266.1 blaOXA-666 Protein Added: WP_114699267.1 blaKPC-36 Protein Added: WP_114699268.1 blaADC-174 Protein Added: WP_114699269.1 blaADC-177 Protein Added: WP_114699270.1 blaADC-178 Protein Added: WP_114699271.1 blaADC-179 Protein Added: WP_114699272.1 blaADC-180 Protein Added: WP_114699273.1 blaOXA-661 Protein Added: WP_114699274.1 blaOXA-662 Protein Added: WP_114699275.1 mcr-8.1 Protein Added: WP_114699276.1 blaOXA-659 Protein Added: WP_114699277.1 blaVIM-60 Protein Added: WP_114699278.1 mcr-5.3 Protein Added: WP_114699279.1 blaOXA-660 Protein Added: WP_114699280.1 blaIMP-76 Protein Added: WP_114699281.1 blaIMP-77 Protein Added: WP_114699282.1 blaIMP-78 Protein Added: WP_114699283.1 blaVIM-59 Protein Added: WP_114699284.1 blaCTX-M-221 - AMR HMM library Changes: Prev. Release: 557 This Release: 563 Removed: 0 Added: 6 HMM Added: NF033648.1 blaOXA-274_like HMM Added: NF033666.1 blaOXA-664_like HMM Added: NF033667.0 blaOXA-55_like HMM Added: NF033669.1 polymyxin_MCR8 HMM Added: NF033670.1 polymyxin_MCR6 HMM Added: NF033671.1 polymyxin_MCR7 - Protein family changes: Prev. Release: 1123 This Release: 1128 Removed: 0 Added: 5 Family Added: - blaOXA-266_fam Family Added: NF033648.1 blaOXA-274_like Family Added: NF033667.1 blaOXA-55_like Family Added: NF033666.1 blaOXA-664_like Family Added: NF033669.1 mcr-8 HMM Added: mcr-6 updated to NF033670.1 mcr-6 HMM Added: mcr-7 updated to NF033671.1 mcr-7 Updates in 2018-07-07.1 - Fix in amr_report.cpp to remove extra field from AMRFinder output Updates in 2018-06-27.1 - Summary: - Protein sequences - Removed 1 protein sequence - Added 290 protein sequences - Changed the names of 2 proteins - Gene families - cfr was reorganized - HMM library - 58 HMMs not in the AMR family hierarchy were removed. They were not used for AMR gene identification so this should have no effect on AMRFinder output. - The polymyxin_MCR3 HMM was updated - Details: Protein Removed: WP_063945333.1 aac(6')-IIa Protein Added: WP_000131886.1 aac(3)-VIa Protein Added: WP_000778180.1 varG Protein Added: WP_001100752.1 blaPER-10 Protein Added: WP_002812372.1 blaOXA-578 Protein Added: WP_002824679.1 blaOXA-595 Protein Added: WP_002837769.1 blaOXA-579 Protein Added: WP_002857546.1 blaOXA-592 Protein Added: WP_002889704.1 blaOXA-591 Protein Added: WP_002936877.1 blaOXA-623 Protein Added: WP_011339581.1 blaRHO Protein Added: WP_011497575.1 blaSHN-1 Protein Added: WP_011550565.1 blaMYX-1 Protein Added: WP_011638903.1 mcr-4.3 Protein Added: WP_012263521.1 mupA Protein Added: WP_012541790.1 blaLEN-28 Protein Added: WP_012698469.1 blaLHK-7 Protein Added: WP_013255389.1 blaSPS-1 Protein Added: WP_013992183.1 blaZOG-1 Protein Added: WP_014206564.1 blaOXA-642 Protein Added: WP_015058260.1 qnrS11 Protein Added: WP_015266427.1 blaECV-1 Protein Added: WP_015431537.1 blaROB-2 Protein Added: WP_015818996.1 blaTTU-1 Protein Added: WP_016252988.1 blaPDC-286 Protein Added: WP_021018581.1 catB8 Protein Added: WP_025006557.1 blaOXA-580 Protein Added: WP_026025287.1 blaALI-1 Protein Added: WP_031192893.1 aadA31 Protein Added: WP_034035338.1 blaPDC-240 Protein Added: WP_035203840.1 catA10 Protein Added: WP_038333643.1 blaEBR-2 Protein Added: WP_038640920.1 qnrB12 Protein Added: WP_041079981.1 erm(44)v Protein Added: WP_041258349.1 blaFIA-1 Protein Added: WP_041385949.1 blaSGM-2 Protein Added: WP_041449074.1 blaANA-1 Protein Added: WP_043774378.1 catA13 Protein Added: WP_043942497.1 blaPST-1 Protein Added: WP_044600959.1 blaOXA-594 Protein Added: WP_044779552.1 blaOXA-638 Protein Added: WP_048236419.1 qnrB85 Protein Added: WP_052259183.1 erm(42) Protein Added: WP_052781249.1 blaOXA-583 Protein Added: WP_052788483.1 blaOXA-611 Protein Added: WP_052788887.1 blaOXA-581 Protein Added: WP_052794776.1 blaOXA-625 Protein Added: WP_052798312.1 blaOXA-609 Protein Added: WP_052800105.1 blaOXA-597 Protein Added: WP_052803794.1 blaOXA-601 Protein Added: WP_052858477.1 blaOXA-637 Protein Added: WP_053872444.1 blaOXA-639 Protein Added: WP_053921012.1 blaOXA-603 Protein Added: WP_057036510.1 blaOXA-629 Protein Added: WP_058157026.1 blaPDC-271 Protein Added: WP_058174497.1 blaPDC-250 Protein Added: WP_058870660.1 blaOXA-651 Protein Added: WP_058951457.1 blaOXA-652 Protein Added: WP_061193431.1 blaPDC-298 Protein Added: WP_064186845.1 qnrS13 Protein Added: WP_065597326.1 blaALI-2 Protein Added: WP_065801616.1 mcr-3.20 Protein Added: WP_065908739.1 qnrB91 Protein Added: WP_070233680.1 blaOXA-614 Protein Added: WP_070698497.1 blaPDC-278 Protein Added: WP_071701819.1 qnrS12 Protein Added: WP_071846333.1 aac(6')_Serra Protein Added: WP_073669325.1 blaPDC-285 Protein Added: WP_075606311.1 blaROB-3 Protein Added: WP_078207746.1 qnrE2 Protein Added: WP_078318620.1 blaROB-4 Protein Added: WP_080699425.1 blaTEM-229 Protein Added: WP_081048762.1 blaMYO-1 Protein Added: WP_081666691.1 blaLHK-1 Protein Added: WP_085843691.1 qnrB95 Protein Added: WP_087696200.1 blaOXA-576 Protein Added: WP_087879616.1 mcr-3.19 Protein Added: WP_088303859.1 blaOXA-624 Protein Added: WP_094308975.1 mcr-3.22 Protein Added: WP_094312656.1 mcr-3.21 Protein Added: WP_094313523.1 mcr-3.23 Protein Added: WP_094321595.1 mcr-3.24 Protein Added: WP_094963248.1 aadA31 Protein Added: WP_096170112.1 qnrS14 Protein Added: WP_096865225.1 blaPER-12 Protein Added: WP_100831609.1 blaPDC-245 Protein Added: WP_103034696.1 blaROB-5 Protein Added: WP_103252528.1 mcr-3.25 Protein Added: WP_104009831.1 blaPER-11 Protein Added: WP_104009832.1 blaPDC-234 Protein Added: WP_104009833.1 blaPDC-235 Protein Added: WP_104009834.1 blaPDC-236 Protein Added: WP_104009835.1 blaPDC-237 Protein Added: WP_104009836.1 blaPDC-238 Protein Added: WP_104009837.1 blaPDC-239 Protein Added: WP_104009838.1 blaPDC-241 Protein Added: WP_104009839.1 blaPDC-242 Protein Added: WP_104009840.1 blaPDC-243 Protein Added: WP_104009841.1 blaPDC-244 Protein Added: WP_104009842.1 blaPDC-246 Protein Added: WP_104009843.1 blaPDC-247 Protein Added: WP_104009844.1 blaPDC-248 Protein Added: WP_104009846.1 blaVIM-56 Protein Added: WP_104009847.1 blaCTX-M-178 Protein Added: WP_104009848.1 blaCTX-M-187 Protein Added: WP_104009849.1 blaCMY-156 Protein Added: WP_104009850.1 mcr-1.12 Protein Added: WP_104009851.1 mcr-7.1 Protein Added: WP_104009852.1 blaIMP-71 Protein Added: WP_104009853.1 blaOXA-575 Protein Added: WP_104009854.1 blaTEM-230 Protein Added: WP_104009855.1 blaTEM-231 Protein Added: WP_104009856.1 blaPDC-227 Protein Added: WP_104009857.1 blaPDC-228 Protein Added: WP_104009858.1 blaPDC-229 Protein Added: WP_104009859.1 blaPDC-230 Protein Added: WP_104009860.1 blaPDC-231 Protein Added: WP_104009861.1 blaPDC-232 Protein Added: WP_104009862.1 blaPDC-233 Protein Added: WP_104531863.1 blaBUT-1 Protein Added: WP_104531864.1 blaBUT-2 Protein Added: WP_104531865.1 blaLHK-2 Protein Added: WP_104531866.1 blaLHK-3 Protein Added: WP_104531867.1 blaLHK-4 Protein Added: WP_104531868.1 blaLHK-5 Protein Added: WP_104531869.1 blaLHK-6 Protein Added: WP_106672612.1 blaCMY-150 Protein Added: WP_106924209.1 blaCTX-M-213 Protein Added: WP_109544237.1 tet(S) Protein Added: WP_109545031.1 dfrA14 Protein Added: WP_109545032.1 qnrB11 Protein Added: WP_109545033.1 vanY-D Protein Added: WP_109545034.1 qnrB22 Protein Added: WP_109545035.1 qacF Protein Added: WP_109545038.1 tet(33) Protein Added: WP_109545039.1 blaSTA-1 Protein Added: WP_109545040.1 chrB Protein Added: WP_109545041.1 aph(3'')-Ib Protein Added: WP_109545042.1 blaORR-1 Protein Added: WP_109545044.1 blaKPC-34 Protein Added: WP_109545045.1 qnrD3 Protein Added: WP_109545046.1 qnrB81 Protein Added: WP_109545047.1 qnrB82 Protein Added: WP_109545048.1 blaOXA-542 Protein Added: WP_109545049.1 blaNDM-20 Protein Added: WP_109545050.1 blaCRH-2 Protein Added: WP_109545051.1 blaCRH-3 Protein Added: WP_109545053.1 blaIMP-73 Protein Added: WP_109545054.1 mcr-4.5 Protein Added: WP_109545055.1 mcr-4.4 Protein Added: WP_109545056.1 mcr-1.13 Protein Added: WP_109545057.1 mcr-5.2 Protein Added: WP_109545058.1 mcr-4.2 Protein Added: WP_109545059.1 blaTEM-232 Protein Added: WP_109545060.1 blaCTX-M-208 Protein Added: WP_109545061.1 blaCTX-M-209 Protein Added: WP_109545062.1 blaCTX-M-210 Protein Added: WP_109545063.1 blaCTX-M-211 Protein Added: WP_109545064.1 blaCTX-M-212 Protein Added: WP_109545065.1 blaCMY-161 Protein Added: WP_109545066.1 blaFOX-16 Protein Added: WP_109545067.1 blaDHA-27 Protein Added: WP_109545068.1 blaDHA-26 Protein Added: WP_109545069.1 blaCTX-M-214 Protein Added: WP_109545070.1 mcr-3.12 Protein Added: WP_109545071.1 blaOXA-649 Protein Added: WP_109545072.1 blaOXA-641 Protein Added: WP_109545073.1 blaFRI-5 Protein Added: WP_109545074.1 blaGPC-1 Protein Added: WP_109545075.1 blaOXA-619 Protein Added: WP_109545076.1 blaOXA-620 Protein Added: WP_109545077.1 blaOXA-636 Protein Added: WP_109545078.1 blaOXA-635 Protein Added: WP_109545079.1 blaOXA-631 Protein Added: WP_109545080.1 blaOXA-626 Protein Added: WP_109545081.1 blaOXA-627 Protein Added: WP_109545082.1 blaOXA-633 Protein Added: WP_109545083.1 blaOXA-628 Protein Added: WP_109545084.1 blaOXA-634 Protein Added: WP_109545085.1 blaOXA-630 Protein Added: WP_109545086.1 blaOXA-632 Protein Added: WP_109545087.1 blaOXA-608 Protein Added: WP_109545088.1 blaOXA-584 Protein Added: WP_109545089.1 blaOXA-585 Protein Added: WP_109545090.1 blaOXA-586 Protein Added: WP_109545091.1 blaOXA-577 Protein Added: WP_109545092.1 blaOXA-587 Protein Added: WP_109545093.1 blaOXA-596 Protein Added: WP_109545094.1 blaOXA-600 Protein Added: WP_109545095.1 blaOXA-588 Protein Added: WP_109545096.1 blaOXA-589 Protein Added: WP_109545097.1 blaOXA-593 Protein Added: WP_109545098.1 blaOXA-599 Protein Added: WP_109545099.1 blaOXA-610 Protein Added: WP_109545100.1 blaOXA-612 Protein Added: WP_109545101.1 blaOXA-598 Protein Added: WP_109545102.1 blaOXA-607 Protein Added: WP_109545103.1 blaOXA-590 Protein Added: WP_109545104.1 blaOXA-604 Protein Added: WP_109545105.1 blaOXA-602 Protein Added: WP_109545106.1 blaOXA-606 Protein Added: WP_109545107.1 blaOXA-582 Protein Added: WP_109545108.1 blaOXA-605 Protein Added: WP_109545109.1 blaOXA-640 Protein Added: WP_109545110.1 blaOXA-616 Protein Added: WP_109545111.1 blaOXA-613 Protein Added: WP_109545112.1 blaOXA-622 Protein Added: WP_109545113.1 blaOXA-618 Protein Added: WP_109545114.1 blaOXA-617 Protein Added: WP_109545115.1 blaOXA-615 Protein Added: WP_109545116.1 blaOXA-621 Protein Added: WP_109791184.1 blaTEM-233 Protein Added: WP_109791185.1 blaPDC-251 Protein Added: WP_109791186.1 blaPDC-252 Protein Added: WP_109791187.1 blaPDC-253 Protein Added: WP_109791188.1 blaPDC-254 Protein Added: WP_109791189.1 blaPDC-255 Protein Added: WP_109791190.1 blaPDC-256 Protein Added: WP_109791191.1 blaPDC-257 Protein Added: WP_109791192.1 blaPDC-258 Protein Added: WP_109791193.1 blaPDC-259 Protein Added: WP_109791194.1 blaPDC-260 Protein Added: WP_109791195.1 blaPDC-261 Protein Added: WP_109791196.1 blaPDC-262 Protein Added: WP_109791197.1 blaPDC-263 Protein Added: WP_109791198.1 blaPDC-264 Protein Added: WP_109791199.1 blaPDC-265 Protein Added: WP_109791200.1 blaPDC-266 Protein Added: WP_109791201.1 blaPDC-267 Protein Added: WP_109791202.1 blaPDC-268 Protein Added: WP_109791203.1 blaPDC-270 Protein Added: WP_109791204.1 blaPDC-272 Protein Added: WP_109791205.1 blaPDC-273 Protein Added: WP_109791206.1 blaPDC-274 Protein Added: WP_109791207.1 blaIMP-74 Protein Added: WP_109791208.1 blaIMP-75 Protein Added: WP_109791209.1 blaCTX-M-216 Protein Added: WP_109791210.1 blaTEM-234 Protein Added: WP_109791211.1 blaCTX-M-217 Protein Added: WP_109791212.1 blaSHV-204 Protein Added: WP_109791213.1 blaNDM-22 Protein Added: WP_109791214.1 blaCTX-M-218 Protein Added: WP_109791215.1 blaCMY-160 Protein Added: WP_109791216.1 blaOXA-654 Protein Added: WP_109997726.1 qnrA9 Protein Added: WP_110092882.1 blaCTX-M-219 Protein Added: WP_111273842.1 mcr-3.13 Protein Added: WP_111273843.1 mcr-3.14 Protein Added: WP_111273844.1 mcr-3.15 Protein Added: WP_111273845.1 mcr-3.16 Protein Added: WP_111273846.1 mcr-3.17 Protein Added: WP_111273847.1 mcr-3.18 Protein Added: WP_111273848.1 blaGES-35 Protein Added: WP_111273849.1 blaGES-36 Protein Added: WP_111273850.1 blaGES-37 Protein Added: WP_111273851.1 blaCMY-162 Protein Added: WP_111273852.1 blaKPC-35 Protein Added: WP_111672883.1 blaPDC-275 Protein Added: WP_111672884.1 blaPDC-294 Protein Added: WP_111672885.1 blaPDC-295 Protein Added: WP_111672886.1 blaPDC-296 Protein Added: WP_111672887.1 blaPDC-297 Protein Added: WP_111672888.1 blaPDC-299 Protein Added: WP_111672889.1 blaPDC-300 Protein Added: WP_111672890.1 blaPDC-276 Protein Added: WP_111672891.1 blaPDC-277 Protein Added: WP_111672892.1 blaPDC-279 Protein Added: WP_111672893.1 blaPDC-280 Protein Added: WP_111672894.1 blaPDC-281 Protein Added: WP_111672895.1 blaPDC-282 Protein Added: WP_111672896.1 blaPDC-283 Protein Added: WP_111672897.1 blaPDC-284 Protein Added: WP_111672898.1 blaPDC-287 Protein Added: WP_111672899.1 blaPDC-288 Protein Added: WP_111672900.1 blaPDC-289 Protein Added: WP_111672901.1 blaPDC-290 Protein Added: WP_111672902.1 blaCTX-M-220 Protein Added: WP_111672903.1 blaPDC-291 Protein Added: WP_111672904.1 blaPDC-292 Protein Added: WP_111672905.1 blaPDC-293 Protein Added: WP_111672906.1 blaCMY-163 Protein Added: WP_111672907.1 blaOXA-657 Protein Added: WP_111672908.1 blaPDC-301 Protein Added: WP_111672909.1 blaPDC-302 Protein Added: WP_111672910.1 blaPDC-303 Protein Added: WP_111672911.1 blaKPC-23 Protein Added: WP_111672912.1 blaNDM-23 Protein Added: WP_111672913.1 blaNDM-24 Protein Added: WP_111672914.1 blaVIM-57 Protein Added: WP_111690897.1 cfr(B) Protein Added: WP_111690898.1 cfr(C) Protein Modified: WP_011987126.1 cfrC updated to WP_011987126.1 cfr-Cb Protein Modified: WP_063854808.1 qnrS updated to WP_063854808.1 qnrS10 HMM Removed: NF000031.1 MFS_efflux_LmrA HMM Removed: NF000040.1 172051428_tet HMM Removed: NF000058.1 Erm41 HMM Removed: NF000060.1 MFS_efflux_LmrB HMM Removed: NF000106.1 40850658_otr HMM Removed: NF000131.1 MATE_multi_MepA HMM Removed: NF000140.3 AAC_6p_Salmo HMM Removed: NF000217.1 MATE_multi_FepA HMM Removed: NF000247.1 MexA HMM Removed: NF000249.1 MexE HMM Removed: NF000250.1 MexH HMM Removed: NF000251.1 MexW-MexI HMM Removed: NF000252.1 MexX HMM Removed: NF000263.1 MATE_multi_NorM HMM Removed: NF000282.2 RND_permease_1 HMM Removed: NF000313.1 adeA-adeI HMM Removed: NF000314.1 adeB HMM Removed: NF000315.1 adeC-adeK-oprM HMM Removed: NF000334.3 drrA HMM Removed: NF000336.1 emrE HMM Removed: NF000342.3 glpA_Cterm HMM Removed: NF000344.1 macA HMM Removed: NF000345.1 macB HMM Removed: NF000349.1 mfpA_AE000516.2 HMM Removed: NF000352.1 norA HMM Removed: NF000357.1 romA HMM Removed: NF000391.1 EmrB HMM Removed: NF010314.2 PRK13751.2 HMM Removed: NF012135.0 ANT_3pp_9_crypt HMM Removed: NF012144.2 ramA_TF HMM Removed: NF012163.2 BaeS_SmeS HMM Removed: NF012168.1 BlaI_of_BCL HMM Removed: NF012198.0 MarA_TF HMM Removed: NF012208.0 SDR_dihy_bifunc HMM Removed: NF012226.0 AdeS_HK HMM Removed: NF012227.0 AdeR_RR HMM Removed: NF012228.1 RobA_TF HMM Removed: NF028537.1 P_eth_NH2_trans HMM Removed: NF030466.0 TIGR02052 HMM Removed: NF030467.0 TIGR02053 HMM Removed: NF033086.2 penta_rpt_Qnr HMM Removed: NF033124.1 estX HMM Removed: NF033134.0 cmlA_floR HMM Removed: NF033138.1 RND-peri-MexC HMM Removed: NF033142.1 efflux_OM_AdeC HMM Removed: NF033143.1 efflux_OM_AdeK HMM Removed: NF033184.1 B3_Acin_new1 HMM Removed: NF033480.1 bifunc_MprF HMM Removed: NF033553.1 MerP_Gpos HMM Removed: NF033555.1 lyase_MerB HMM Removed: NF033556.1 MerTP_fusion HMM Removed: NF033560.1 merT_RC607 HMM Removed: NF033565.0 trans_MerF HMM Removed: NF033606.1 heat_AAA_ClpK HMM Removed: NF033607.0 disagg_AAA_ClpG HMM Removed: NF033617.1 RND_permease_2 HMM Removed: NF033627.1 intimin_all HMM Removed: NF033636.1 acid_shock_Asr HMM Modified: NF033408.2 polymyxin_MCR3 updated to NF033408.5 polymyxin_MCR3 Family Removed: - cfrC Family Added: - cfr(B) Family Added: - cfr(C) Family Added: - cfr-Cb Family Changed: NF033408.2 mcr-3 updated to NF033408.5 mcr-3 --------------------------------------------------------------------- Changes included in 2018-05-15.1 --------------------------------------------------------------------- - Data Changes: Protein Removed: WP_010886396.1 lmr(B) HMM Added: NF033614.1 APH_6_Ic_gen HMM Added: NF033617.1 RND_permease_2 HMM Added: NF033626.1 blaBKC_GPC HMM Added: NF033627.1 intimin_all HMM Added: NF033636.1 acid_shock_Asr HMM Modified: NF000011.1 APH_6_Ic updated to NF000011.2 APH_6_Ic HMM Modified: NF000221.3 FosA updated to NF000221.4 FosA HMM Modified: NF000282.1 RND_permease_1 updated to NF000282.2 RND_permease_1 HMM Modified: NF000428.2 blaFRI updated to NF000428.4 blaFRI HMM Modified: NF033582.0 blaALI updated to NF033582.2 blaALI Family Removed: NF000060.1 lmr(B) Family Added: NF033626.1 blaBKC_GPC Family Added: - blaGPC - Algorithm Changes: - Partial proteins identified as "Method" PARTIAL if length of blast alignment > 50% and < 90% of database protein. --------------------------------------------------------------------- Changes included in 2018-05-08.1 RELEASE CANDIDATE --------------------------------------------------------------------- - Addition of handling for genbank plasmid gff --------------------------------------------------------------------- Changes included in 2018-04-16.1 --------------------------------------------------------------------- - Addition of file format checking for FASTA and GFF files before AMRFinder blast and HMM searches are run - Altered format of fam.tab file to include NF accessions for families - Removal of non-reportable families from fam.tab